Not provided
Not provided
Not provided
Not provided
Not provided
DSMB estimated futility of the trial and safety risk
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to determine whether an infusion of lidocaine/ketamine compared to fentanyl is equivalent in anesthesia effectiveness and can help reduce the incidence of postoperative nausea and vomiting in patients undergoing elective hip arthroscopy surgery.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| lidocaine/ ketamine infusion | Experimental | lidocaine 1mg/Kg bolus, followed by continuous infusion 1 mg/kg/h AND ketamine 1mg/Kg bolus followed by continuous infusion 1 mg/kg/h |
|
| fentanyl | Active Comparator | iv fentanyl, 3ug/kg bolus |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lidocaine/ ketamine | Drug |
| ||
| Fentanyl |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of postoperative nausea and vomiting in the recovery room | first 3 postoperative hours | |
| morphine consumption in the recovery room | first 3 postopeartive hours |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of postoperative nausea and vomiting on day 1 | 1st postoperative day | |
| Anesthestic gas consumption | intraoperative |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| David Torres, MD; MSc | Clinica Santa Maria | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinica Santa Maria | Santiago | Chile |
Not provided
| ID | Term |
|---|---|
| D008012 | Lidocaine |
| D007649 | Ketamine |
| D005283 | Fentanyl |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Aniline Compounds |
| D000588 | Amines |
| D003510 | Cyclohexanes |
| D003516 | Cycloparaffins |
| D006840 | Hydrocarbons, Alicyclic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |