Preliminary Study for Selective Detection of the CD8+ Myelin Specific T Cell in the Blood of Multiple Sclerosis Patients (MS).
Preliminary Study for Selective Detection of the CD8+ Myelin Specific T Cell in the Blood of Multiple Sclerosis Patients (MS).
Most experts in the field consider Multiple Sclerosis as the main auto immune disease of the central nervous system. In spite of many works, the data in the literature concerning the antigens targeted by the CD8+ T-Cell response are still contradictory and insufficient.
30 patients distributed in 3 groups of 10 patients with specific inclusion criteria will participate in this trial:
The aim of this clinical trial is to detect the CD8+ myelin specific T-Cells in the blood of Multiple Sclerosis patients.
Inclusion Criteria:
Group 1: HLA-A2 patients whose Multiple Sclerosis has just been diagnosed
Group 2: HLA-A2 patients hospitalized in the neurology department who are not affected with a neuroimmunological disorder
Group 3: HLA-A2 Multiple Sclerosis patients treated by Natalizumab therapy
Exclusion Criteria:
Group 1 and 3:
Group 2: