The Role of Biomarker in Serum, Cerebrospinal Fluid and Parenchyma in the Context of Aneurysmal Subarachnoid Hemorrhage.

Die Rolle Der Biomarker in Serum, Liquor Und Parenchym im Rahmen Der Aneurysmatischen Subarachnoidalblutung: Verlauf Und Korrelation zu Therapie Und Outcome - bioSAB -

The aim of this study is to improve the usability of biomarkers for the timely prediction of new complications following a cerebral hemorrhage, especially in combination with invasive, functional and local measurements for patients with aneurysmal subarachnoid hemorrhage (SAH). Based on analyzed biomarker profiles the chosen therapy efforts are assessed in their immediate and longer-term effectiveness.

Inclusion Criteria:

• male or female, age ≥ 18 years
• signed consent for participation in the study
• signed consent for further analysis of the samples collected during the clinical routine
• in-patients

Exclusion Criteria:

• female or male patient <18 years
• pregnancy, lactation
• lack of signed informed consent for participation in the study
• lack of signed consent for the further analysis of the samples collected during the clinical routine
• taking a study drug within the last thirty days
• Simultaneous participation in another clinical trial (except participation as control group)
• persons who are in a dependent relationship or employment with the sponsor or investigator
• persons housed for a judicial or administrative order in an institution