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Laparoscopic Ovarian Drilling is a valid procedure for infertile anovulatory women with polycystic ovarian syndrome who failed to get pregnant or to ovulate with ovulation induction medications as clomiphene citrate or exogenous gonadotropins. The reasearchers supposed that endometrial curettage at time of laparoscopic ovarian drilling may boost fertility in these women.
Current literature suggests that endometrial biopsy may improve pregnancy rates in infertile women hence the investigators will examine whether this hypothesis will apply to infertile PCOS women undergoing laparoscopic ovarian drilling to overcome ovulatory disfunction or not.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Currettage | Experimental | Endometrial Currettage (endometrial scrapping) will be performed at the time of laparoscopic ovarian drilling |
|
| Nothing | No Intervention | No endometrial curettage at time of Laparoscopic ovarian drilling |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endometrial Currettage | Procedure | Only Laparoscopic ovarian drilling without endometrial currettage will be performed |
|
| Measure | Description | Time Frame |
|---|---|---|
| live birth rate per woman randomized | 15 months |
| Measure | Description | Time Frame |
|---|---|---|
| pregnancy rate per woman randomised | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| miscarriage rate time to pregnancy interval | 6 months |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed Gibreel, MD | Contact | 00201004045733 | ahmedfathgi@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Ahmed Gibreel, MD | Mansoura University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mansoura University Teaching Hospital | Recruiting | Al Mansurah | 53111 | Egypt |
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| ID | Term |
|---|---|
| D007246 | Infertility |
| D011085 | Polycystic Ovary Syndrome |
| ID | Term |
|---|---|
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D010048 | Ovarian Cysts |
| D003560 | Cysts |
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| D009369 |
| Neoplasms |
| D010049 | Ovarian Diseases |
| D000291 | Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D006058 | Gonadal Disorders |
| D004700 | Endocrine System Diseases |