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The investigators will collect plasma samples at baseline, during treatment, and at progression.
In this study, the investigators will collect plasma samples at baseline, during treatment, and at progression. This plasma bank will be used to study the potential value of some biomarkers to predict treatment activity or resistance to cetuximab or other targeted agents
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No treatment | Patients with squamous cell carcinoma of the head and neck, targeted therapies, plasma samples:
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plasma samples | Other | Plasma samples at baseline (and one whole blood sample) and at every radiological evaluations |
|
| Measure | Description | Time Frame |
|---|---|---|
| Prospective storage of plasma samples of patients treated with cetuximab or other targeted agents | All the analyses will be done when we have enough of collected samples | one year after the collection |
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Inclusion Criteria:
Exclusion Criteria:
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PATIENTS TREATED WITH MOLECULAR TARGETED THERAPIES FOR SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jean-Pascal Machiels, MD, PhD | Contact | 0032 2 764 | 5457 | jean-pascal.machiels@uclouvain.be |
| Séverine Carlier, MD | Contact | 0032 2 764 | 47849 | severine.carlier@uclouvain.be |
| Name | Affiliation | Role |
|---|---|---|
| Jean-Pascal Machiels, MD, PhD | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinique Saint-Pierre | Recruiting | Ottignies | Brabant Wallon | 1340 | Belgium |
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| ID | Term |
|---|---|
| D000077195 | Squamous Cell Carcinoma of Head and Neck |
| ID | Term |
|---|---|
| D002294 | Carcinoma, Squamous Cell |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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One EDTA tube is collected at the beginning of the study and there are only plasma samples at baseline, during treatment, and at progression.
| Grand Hôpital de Charleroi | Recruiting | Charleroi | Hainaut | 6000 | Belgium |
|
| Centre Hospitalier Jolimont-Lobbes-Nivelles-Tubize | Recruiting | Haine-Saint-Paul | 7100 | Belgium |
|
| CHU Liège | Recruiting | Liège | 4000 | Belgium |
|
| Clinique et Maternité Sainte-Elisabeth | Recruiting | Namur | 5000 | Belgium |
|
| D009369 | Neoplasms |
| D006258 | Head and Neck Neoplasms |
| D009371 | Neoplasms by Site |