Effect of Bariatric Surgery on Kidney Function

Effect of Bariatric Surgery on Kidney Function

Primary hypothesis:

A large reduction in weight is not associated with a change in accurately measured glomerular filtration rate (GFR) (51Chromium ethylenediaminetetraacetic acid plasma clearance (51Cr-EDTA)).

Secondary hypothesis:

A large reduction in weight is associated with a greater change in estimated GFR (The Modification of Diet in Renal Disease (MDRD-formula)) than in accurately measured GFR.

Other formulas for estimated GFR (Cockcroft Gault, Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), CKD-EPI with cystatin C) are better correlated with accurately measured GFR.

Inclusion Criteria:

• Male or female, older than 18 years of age
• Appointed to gastric by-pass surgery on Hvidovre Hospital, Denmark

Exclusion Criteria:

• Withdrawal of surgical indication
• Severe oedema or ascites