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Based on a business decision unrelated to any safety concerns.
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This study is being done to determine the long-term safety and possible benefits of transplanted Human Central Nervous System Stem Cells (HuCNS-SC) for patients with Geographic Atrophy of Age-Related Macular Degeneration. This long-term follow-up study is limited to those individuals who received a transplant of HuCNS-SC cells into one of their eyes as part of the CL-N01-AMD study. No additional study product will be given in this 4-year long-term follow-up study.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Human Central Nervous System Stem Cells | Biological |
|
| Measure | Description | Time Frame |
|---|---|---|
| Frequency and types of serious adverse events | At each of 11 visits over a period of 48 months |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency and types of adverse events | At each of 11 visits over a period of 48 months |
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Inclusion Criteria:
Exclusion Criteria:
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All subjects with age-related macular degeneration (AMD) with GA who received transplantation of HuCNS-SC in Study CL-N01-AMD.
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| Name | Affiliation | Role |
|---|---|---|
| David Birch, Ph.D. | Principal Investigator | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | United States |
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| ID | Term |
|---|---|
| D008268 | Macular Degeneration |
| D057092 | Geographic Atrophy |
| ID | Term |
|---|---|
| D012162 | Retinal Degeneration |
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
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