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Study site change
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| Name | Class |
|---|---|
| Sichuan J.Z. Bio-chemical Science and Technology Development Co., Ltd | INDUSTRY |
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The purpose of the study is to explore if chlorogenic acid is safe in patients with cancer.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| chlorogenic acid | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| chlorogenic acid | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of adverse events | within the first 60 days after the first dose of chlorogenic acid |
| Measure | Description | Time Frame |
|---|---|---|
| dose-limiting toxicity | within the first 30 days after the first dose of chlorogenic acid | |
| maximum tolerated dose | within the first 30 days after the first dose of chlorogenic acid | |
| Measure | Description | Time Frame |
|---|---|---|
| Change in number of red blood cell and level of hemoglobin | within 1 year after the first dose of chlorogenic acid | |
| change in the diameters of lymph node metastasis | within 1 year after the first dose of chlorogenic acid |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yuankai Shi, Dr. | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Principal Investigator |
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| ID | Term |
|---|---|
| D002726 | Chlorogenic Acid |
| ID | Term |
|---|---|
| D002934 | Cinnamates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
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| Area under the plasma concentration versus time curve (AUC) and Peak Plasma Concentration (Cmax) of chlorogenic acid |
| within the first 30 days after the first dose of chlorogenic acid |
| improvement in cancer-related symptoms and quality of life | within 1 year after the first dose of chlorogenic acid |
| change in levels of tumor markers | within 1 year after the first dose of chlorogenic acid |
| D003509 |
| Cyclohexanecarboxylic Acids |