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| ID | Type | Description | Link |
|---|---|---|---|
| R00MH090243 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
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The purpose of this study is to test the effects of a computerized approach/avoidance training (AAT) procedure in a sample of individuals diagnosed with social anxiety disorder (SAD). The training procedure is designed to modify automatic approach responses for positive social stimuli. Previous research has shown that a single administration of approach-positive AAT influences social behavior in the laboratory. The goal of this study is to examine the effects of a four-session AAT procedure on measures of positive social-emotional functioning. The investigators hypothesize that individuals assigned to the approach-positive AAT condition will demonstrate larger increases in positive affect and improvements in social relationship functioning from pre- to post-assessment compared to those assigned to the control condition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Approach-positive AAT | Experimental | Participants will receive 4 sessions over 2 weeks of a computerized AAT procedure designed to increase automatic approach responses for positive social cues. |
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| Control AAT | Placebo Comparator | Participants will receive 4 sessions over 2 weeks of a computerized AAT procedure in which there is no contingency between arm movement and positive social cues. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Approach-positive AAT | Behavioral |
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| Control AAT |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in positive affect (Positive and Negative Affect Schedule) | Change from pre- to post-assessment in positive affect. | 1 month |
| Change from baseline in social connectedness (Social Connectedness Scale - Revised) | Change from pre- to post-assessment in social connectedness. | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in social relationship functioning (Interpersonal Outcomes Scale) | Change from pre- to post-assessment in frequency of social approach behaviors and relationship satisfaction. | 1 month |
| Change from baseline in social anxiety symptoms (Liebowitz Social Anxiety Scale) |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in blood oxygen level dependent (BOLD) response in the striatum, amygdala, and medial prefrontal cortex, as measured with functional magnetic resonance imaging (fMRI) | Change from pre- to post-assessment in neural activation during social reward processing. | 1 month |
| Change from baseline in social anxiety disorder (SAD) related psychopathology, including depression and anhedonia. |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Charles T Taylor, PhD | University of California, San Diego | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California, San Diego; Psychiatry Clinical Research | San Diego | California | 92037-0855 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40657593 | Derived | Hunt C, Caudle MM, Paulus MP, Stein MB, Taylor CT, Bomyea J. Reduced neural activation during positive social approach is associated with better response to approach avoidance training for social anxiety disorder. J Mood Anxiety Disord. 2025 Feb 7;10:100110. doi: 10.1016/j.xjmad.2025.100110. eCollection 2025 Jun. | |
| 36549342 | Derived | Bomyea J, Sweet A, Davey DK, Boland M, Paulus MP, Stein MB, Taylor CT. Randomized controlled trial of computerized approach/avoidance training in social anxiety disorder: Neural and symptom outcomes. J Affect Disord. 2023 Mar 1;324:36-45. doi: 10.1016/j.jad.2022.12.054. Epub 2022 Dec 19. |
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| ID | Term |
|---|---|
| D000072861 | Phobia, Social |
| ID | Term |
|---|---|
| D010698 | Phobic Disorders |
| D001008 | Anxiety Disorders |
| D001523 | Mental Disorders |
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Change from pre- to post-assessment in social anxiety symptoms. |
| 1 month |
Change from pre- to post-assessment in symptoms of depression and anhedonia |
| 1 month |