Clinical Value of Noninvasive Intracranial Pressure Measurement

Scientific Research and Development of Innovative Evidence Based Non-invasive Brain Diagnostic and Monitoring Solutions for Neurological and Traumatic Brain Injury Patients

The aim of the study is to evaluate accuracy and precision of non-invasive intracranial pressure measurement device (Vittamed 205) for selected patients compared with cerebrospinal fluid pressure measured during lumbar puncture

Non-invasive intracranial pressure (ICP) measurements with Vittamed 205 aICP meter will be compared to simultaneous cerebrospinal fluid (CSF) pressure measurements during lumbar puncture. Measures of pressure in mmHg will be compared. These measurements will be compared in chronic daily headache, normal pressure hydrocephalus and multiple sclerosis patients groups. For stroke patients noninvasive measurements will be compared with cerebral lesion in brain MRI/CT.

Inclusion Criteria:

• Chronic daily headache with suspected idiopathic intracranial hypertension
• Diagnosed of suspected multiple sclerosis (MS)
• Intracranial hemorrhage/ stroke

Exclusion Criteria:

• Patient not able to understand information about the trial
• Uncooperative patient
• Intracranial hemorrhage volume <20 or >40ml
• Stroke area larger than 1/3 of the middle cerebral artery