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| Name | Class |
|---|---|
| Fazer Group | INDUSTRY |
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The evidence linking chocolate with lowered blood pressure has been observed. However, the interventions have been short, at most 4 weeks. The aim of this study is to find out if the habitual consumption of dark chocolate for 8 weeks has an effect on blood pressure. Also, more insight to the mechanisms linking chocolate to individual healt-responses is needed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dark chocolate, dietary counselling | Experimental | Mildly hypertensive subject will replace their usual snacks with with 50 g dark chocolate daily for a period of 8 weeks. |
|
| Dietary counselling | Active Comparator | Usual snacks are limited. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dark chocolate | Dietary Supplement | Mildly hypertensive subject will replace their usual snacks with with 50 g dark chocolate daily for a period of 8 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in systolic and diastolic blood pressure | Usual daily snack is replaced by 50 g dark chocolate for a period of 8 weeks. During the control period, the same usual snack is limited in the diet, but without the replacement with the dark chocolate. | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Ambulatory blood pressure | 8 weeks | |
| Blood lipids, inflammation markers, plasma levels of cocoa polyphenols | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mikael Fogelholm, Dr. | University of Helsinki | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Helsinki | Helsinki | Helsingin Yliopisto | 00014 | Finland | ||
| Institute of Clinical Medicine |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26296850 | Derived | Koli R, Kohler K, Tonteri E, Peltonen J, Tikkanen H, Fogelholm M. Dark chocolate and reduced snack consumption in mildly hypertensive adults: an intervention study. Nutr J. 2015 Aug 22;14:84. doi: 10.1186/s12937-015-0075-3. |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| Dietary counselling | Other | Usual snacks are limited. |
|
| Helsinki |
| Uusimaa |
| 00290 |
| Finland |