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The limaprost alfadex can improve the surgical outcomes in patients with cervical myelopathy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Limaprost | Experimental | taking Limaprost α-Cyclodextrin Clathrate 1 Tablets (166.67 μg), three times per day |
|
| Control | Placebo Comparator | taking placebo drug |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Limaprost | Drug | taking Limaprost α-Cyclodextrin Clathrate 1 Tablets (166.67 μg), three times per day |
|
| Measure | Description | Time Frame |
|---|---|---|
| Japanese Orthopedic Association (JOA) recovery rates | JOA recovery rate = [(postoperative JOA score) - (preoperative JOA score)] / [(17-(preoperative JOA score)] x 100 (%). | up to 12 months after operation |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Pain Scale for neck pain | up to 12 months after operation | |
| Neck disability index score | up to 12 months after operation | |
| Japanese orthopaedic association Cervical Myelopathy Evaluation Questionnaire score |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jin S. Yeom | Seoul National University Bundang Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do | 463-707 | South Korea |
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| ID | Term |
|---|---|
| C059238 | limaprost |
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| Placebo | Drug | taking placebo drug |
|
| up to 12 months after operation |
| Questionnaire Short Form 12 | up to 12 months after operation |
| Japanese orthopaedic association score | up to 12 months after surgery |
| assessment of the efficacy of positron emission tomography (PET) | The assessment of the efficacy of PET for prediction of drug (Limaprost) effect | up to 12 months after operation |