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Transcranial direct current stimulation is a tool to modulate cortical excitability.
Anodal transcranial direct currenti stimulation over visual cortex is able to decrease the thermo-nociceptive sensibility and thermonociceptive potentials, whilst cathodal transcranial direct current stimulation has the opposite effect, it decreases VEP amplitude and habituation. This neuromodulation technique is probably a tool in the prevention in episodic and chronic migraine.
The aim of the study is to study short and long term effect of tDCS over pain treshold, contact heat evoked potentials, blink reflex and visual evoked potentials in healthy volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cefaly tDCS | Experimental | Cathodal Cefaly tDCS is delivered over the visual cortex at 2 mA of intensity, for 20 minutes, for 5 consecutive days in 9 HV. The anode is placed over the left DLPFC. 2 mA anodal tDCS is delivered over the visual cortex, for 20 minutes, for 5 consecutive days in 9 HV |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cefaly tDCS | Device | Cefaly tDCS (transcranial direct current stimulation) is able to modify cortical excitability, in particular anodal tDCS increases it. The side effects of tDCS are minor, especially sensations of itching and scalp paresthesias. |
| Measure | Description | Time Frame |
|---|---|---|
| Neurophysiological mesures changes | Modifications in neurophysiological test after direct current stimulation | up to 1 month |
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| Measure | Description | Time Frame |
|---|---|---|
| VEP changes | Evaluation of changes in latency, amplitude, slope and habituation | up to 1 month |
| Blink changes | Evaluation of changes in latency, amplitude, slope and habituation |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Delphine Magis, MD | University of Liege | Principal Investigator |
| Jean Schoenen, MD | University of Liege | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Roberta Baschi | Liége | Liége | 4000 | Belgium |
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| up to 1 month |
| CHEPS changes | Evaluation of changes in latency, amplitude, slope and habituation | up to 1 month |
| Quantitave Sensory Testing | Evaluation of changes in thresholds | up to 1 month |