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In animal and human studies, histochemical and physiological evidences showed that the muscle transferred from slow, fatigue-resistant muscle to fast, fatigable muscle after spinal cord injury. The alternation of muscular property was accompanied by the alternation of spinal circuitry property, and was related to the immobilization adaptation. Previous study showed that remobilization by continuous passive motion (CPM) for one month would restore the function of spinal circuitry in individual with chronic SCI. It is possible that long term application of CPM can reverse the adaptation of contractile properties of the paralyzed muscle after SCI. The purpose of this study is to investigate the effect of a four month CPM training on muscular properties in individuals with chronic SCI.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SCI | Experimental | SCI participated in a 4-month robot-assisted passive ankle exercise regimen. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ankle continuous passive motion machine. | Procedure | A rehabilitation program of machine driven passive stretch exercise on ankle. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The contractile properties of the muscles | Measure of changes in contractile properties of soleus and tibialis anterior | Baseline, 1 month, 2 months, 3 months, and 4 months |
| Fatigue index | Measure of changes in Fatigue index of soleus and tibialis anterior. | Baseline, 1 month, 2 months, 3 months, and 4 months |
| Clinical muscle tone tests | Measure of changes in clinical muscle tone tests of soleus and tibialis anterior by Modified Ashworth Scale. | Baseline, 1 month, 2 months, 3 months, and 4 months |
| Patient Reported Impact of Spasticity Measure (PRISM) | Measure of changes in PRISM. | Baseline, 1 month, 2 months, 3 months, and 4 months |
| The potential adverse effects of ankle swelling | Measure of changes in the potential adverse effects of ankle swelling. | Baseline, 1 month, 2 months, 3 months, and 4 months |
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Inclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chang Gung University | Taoyuan | 333 | Taiwan |
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| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| D009122 | Muscle Hypertonia |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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