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Percutaneous nephrostomy (PCN) is one of the interventions in the radiology department in which pain control is necessary. Quadratus Lumborum (QL) block will be tried to limit the use of systemic analgesics and its accompanying untoward effects in those frail patients requiring PCN that is performed in the prone position.
Quadratus Lumborum block is a novel technique in which extension into the thoracic paravertebral space may occur. QL block would seem to be able to alleviate both somatic and visceral pain so it's expected to decrease the need for systemic sedation\analgesia to a minimum.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Local Anesthetic infiltration and MAC | Active Comparator |
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| Quadratus Lumborum block and MAC | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Local Anesthetic infiltration | Procedure | Lignocaine infiltration through the nephrostomy track |
|
| Measure | Description | Time Frame |
|---|---|---|
| Analgesia | Verbal Rating Scale is assessed for degree of pain during the procedure and after till discharge from the radiology department. | 4 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory Depression | Respiratory rate and airway patency is monitored with an anesthesiologist. | 4 hours |
| Sedation | Ramsay Seadation Score is assessed during and after procedure till discharge |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dina N Abbas, M D | National Cancer Institute, Egypt | Study Director |
| Ghada M Bashandy, MD | National Cancer Institute, Egypt | Principal Investigator |
| Wael Darwish, M D | National Cancer Institute, Egypt | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cancer Institute | Cairo | Old Cairo | 11796 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24249997 | Result | Kadam VR. Ultrasound-guided quadratus lumborum block as a postoperative analgesic technique for laparotomy. J Anaesthesiol Clin Pharmacol. 2013 Oct;29(4):550-2. doi: 10.4103/0970-9185.119148. | |
| 24310051 | Result | Ironfield CM, Barrington MJ, Kluger R, Sites B. Are patients satisfied after peripheral nerve blockade? Results from an International Registry of Regional Anesthesia. Reg Anesth Pain Med. 2014 Jan-Feb;39(1):48-55. doi: 10.1097/AAP.0000000000000038. |
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| ID | Term |
|---|---|
| D001733 | Bites and Stings |
| D009369 | Neoplasms |
| ID | Term |
|---|---|
| D011041 | Poisoning |
| D064419 | Chemically-Induced Disorders |
| D014947 | Wounds and Injuries |
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| ID | Term |
|---|---|
| D008012 | Lidocaine |
| D000077554 | Levobupivacaine |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
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| Quadratus Lumborum block | Procedure | A linear 12-MHz ultrasound probe will be placed in the anterior axillary line to visualize the typical triple abdominal layers. Then, the probe will be placed in the midaxillary line and at this point the layers of abdominal layers starte to taper. The probe will be placed in the posterior axillary line, sonoanatomy will show first the transversus abdominis disappearing then the internal oblique and external oblique forming aponeurosis and appearance of QL will be noticed. At the posterior border of the quadratus lumborum muscle and outside the fascia, Touhe needle will be inserted in plane and confirmed its position by injecting saline. Under ultrasound (US) guidance, local anesthetic mixure will be deposited separating the fascia |
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| MAC | Drug | Incremental doses are given to the targed sedation and analgesia |
|
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| 4 hours |
| Cardiovascular stability | Blood pressure and Heart rate is assessed during and after procedure till discharge | 4 hours |
| Patient Satisfaction | Patient Satisfaction Quistionaire | 48 hours |
| Aniline Compounds |
| D000588 | Amines |
| D002045 | Bupivacaine |