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Objective and background: The aim of this study is to evaluate the clinical outcome of using the hyaluronic acid gel in reconstructing inter-dental papillae at the aesthetic zones in a follow-up period of six months.
Materials and Methods: 30 interdental papilla deficiencies which would meet the the inclusion criteria will be evaluated. After applying local anesthesia, 0.2 ml hyaluronic acid gel will be injected at the affected areas. This procedure will be repeated 3 times for the evaluated areas. Photographs will be taken before injection this material, and at 3 and 6 months following the intervention.
The presence or absence of the interproximal papilla is essential concern to periodontists, restorative dentists, and to the patients. The loss of papilla can cause cosmetic deformities (black triangles), phonetic problems, and food debris accumulation. Often the loss of papilla is a consequence of periodontal disease because of gingival inflammation, attachment loss and interproximal bone height resorption.
Several reasons also lead to absence of interdental papillae including:
1) Plaque associated lesions, 2) Traumatic oral hygiene procedures, 3) Abnormal tooth shape, 4) Improper contours of the restoration, 5) Spacing between teeth, 6) Loss of teeth.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Affected Interdental Papillae Group | This is the only group in which the material will be used |
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| Measure | Description | Time Frame |
|---|---|---|
| Percentage of change in papillary height (PCPH) from baseline measurement | The treated sites will be examined, defect measurements will be recorded, and photographs will be taken at a standard (1:1) magnification. The measurement of the distance from the tip of the interdental papilla to the base of the contact area for each study lesion separately using specific software. | T0: baseline assessment, T1: immed. following injection, T2: after 3 weeks, T3: immed. following 2nd injection if required, T4: after 6 weeks from T1, T5: immed. following 3rd injection if needed, T6: after 3 months, T7: after 6 months postoperatively. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the Interdental Papilla Index Score (CPIS) from baseline measurement | The treated sites will be examined clinically, using a periodontal probe | T0: baseline assessment, T1: immed. following injection, T2: after 3 weeks, T3: immed. following 2nd injection if required, T4: after 6 weeks from T1, T5: immed. following 3rd injection if needed, T6: after 3 months, T7: after 6 months postoperatively. |
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Inclusion Criteria:
The patient should be:
Defected interdental papilla criteria:
Exclusion Criteria:
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Patients will be recruited from the database of Periodontics Department at University of Damascus. A random sample of 30 patients will be included in this evaluation study from those who have been identified with defected interdental papillae.
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| Name | Affiliation | Role |
|---|---|---|
| Tarek Ata Dalal, DDS | MSc student, Department of Periodontology, University of Damascus Dental School | Principal Investigator |
| Suleiman Dayoub, DDS MSc PhD | Associate Professor of Periodontics, Department of Periodontics, University of Damascus Dental School, Damascus | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Periodontics, University of Damascus Dental School | Damascus | Rif-dimashq Governorate | DM20AM18 | Syria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 2640208 | Background | Agudio G, Pini Prato GP, Nevins M, Cortellini P, Ono Y. Esthetic modifications in periodontal therapy. Int J Periodontics Restorative Dent. 1989;9(4):288-99. No abstract available. | |
| 1058834 | Background | Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J. 1975 Dec;25(4):229-35. |
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| 4509004 | Background | Angelopoulos AP, Goaz PW. Incidence of diphenylhydantoin gingival hyperplasia. Oral Surg Oral Med Oral Pathol. 1972 Dec;34(6):898-906. doi: 10.1016/0030-4220(72)90228-9. No abstract available. |
| 19843105 | Background | Becker W, Gabitov I, Stepanov M, Kois J, Smidt A, Becker BE. Minimally invasive treatment for papillae deficiencies in the esthetic zone: a pilot study. Clin Implant Dent Relat Res. 2010 Mar;12(1):1-8. doi: 10.1111/j.1708-8208.2009.00247.x. Epub 2009 Oct 16. |
| 15643586 | Background | Biesman B. Soft tissue augmentation using Restylane. Facial Plast Surg. 2004 May;20(2):171-7; discussion 178-9. doi: 10.1055/s-2004-861760. |
| 17317557 | Background | Brandt FS, Cazzaniga A. Hyaluronic acid fillers: Restylane and Perlane. Facial Plast Surg Clin North Am. 2007 Feb;15(1):63-76, vii. doi: 10.1016/j.fsc.2006.11.002. |
| 9497723 | Background | Jemt T. Regeneration of gingival papillae after single-implant treatment. Int J Periodontics Restorative Dent. 1997 Aug;17(4):326-33. |