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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-A01062-43 | Other Identifier | IDRCB |
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To assess the impact and to identify the main risk factors for psychological and cardiac morbidity (post-traumatic stress disorder, anxiety and depression) in case of postpartum hemorrhage
The HELP- MOM study is an observational study that seeks to identify the major determinants of morbidity induced by postpartum hemorrhage (PPH) in the short and medium term. Even if PPH remains the leading cause of death in the world and in France , its main impact in so-called developed countries is not so much maternal mortality ( which is very small ) but induced morbidity.Data from the literature suggest that in a number of cases, PPH is associated with cardiac abnormalities. The nature of the abnormalities, their potential impact on the functioning of the cardiovascular system of women and their evolution over time (possibility of persistent sequelae) are not known. Similarly, it is known that the postpartum period of normal pregnancy followed by a normal delivery is at risk of psychological disorders in the mother. The PPH is a very serious situation where sometimes the vital prognosis of the mother was committed. Again, determining the exact nature and consequences of psychological harm secondary PPH are not known. Finally, fertility and the risk of recurrence after an episode PPH are also poorly understood. Outside hysterectomy hemostasis which permanently affects the fertility of the patient, the severity and type of management of PPH most likely affect fertility. Only a long-term monitoring could help address this issue. Thus, HELP MOM - study aims to address these issues. To do this, HELP MOM, was divided into two sub- studies : 1) HELP-MOM 1 "multidisciplinaire" which corresponds to the cohort of patients in whom psychological state will be studied in the immediate waning PPH then during a 6 months through appropriate questionnaires , 2 ) HELP-MOM 2 "cardio" that corresponds to the cohort of patients who experienced a cardiac abnormality in the initial management and will therefore be included in a cardiac monitoring.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HELPMOM1 | corresponds to the cohort of patients in whom psychological state will be studied in the immediate waning PPH then during a 6 months through appropriate questionnaires | ||
| HELPMOM2 | corresponds to the cohort of patients enrolled in group HELPMOM1 who experienced a cardiac abnormality in the initial management and will therefore be included in a cardiac monitoring |
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| Measure | Description | Time Frame |
|---|---|---|
| Identification of risk factors for psychological impact of PPH | Identification of risk factors for psychological impact of PPH, as measured three questionnaires (HELPMOM1) | 1 month |
| Occurrence of a cardiac event | Occurrence of a cardiac event, defined as an elevation of troponin or BNP or an EKG modification during the acute phase of postpartum hemorrhage (PPH) (HELPMOM2) | Day0 |
| Identification of risk factors for psychological impact of PPH | Identification of risk factors for psychological impact of PPH, as measured three questionnaires (HELPMOM1) | 3 months |
| Identification of risk factors for psychological impact of PPH | Identification of risk factors for psychological impact of PPH, as measured three questionnaires (HELPMOM1) | 6 months |
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Inclusion Criteria:
HELPMOM1 :
HELPMOM2 :
Enrolled HELMOM1
Presence of one or more items from the following list at the moment of PPH:
Exclusion Criteria:
HELPMOM1:
HELPMOM2:
- Patient with pace maker
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Patients with postpartum hemorrhage
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| Name | Affiliation | Role |
|---|---|---|
| Etienne GAYAT, MD, PhD | Assistance Publique - Hôpitaux de Paris | Study Chair |
| Alexandre MEBAZAA, MD, PhD | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Département Anesthésie et Réanimation - Hôpital Lariboisière | Paris | 75010 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38128731 | Derived | Deniau B, Ricbourg A, Weiss E, Paugam-Burtz C, Bonnet MP, Goffinet F, Mignon A, Morel O, Le Guen M, Binczak M, Carbonnel M, Michelet D, Dahmani S, Pili-Floury S, Ducloy Bouthors AS, Mebazaa A, Gayat E. Association of severe postpartum hemorrhage and development of psychological disorders: Results from the prospective and multicentre HELP MOM study. Anaesth Crit Care Pain Med. 2024 Apr;43(2):101340. doi: 10.1016/j.accpm.2023.101340. Epub 2023 Dec 19. |
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| ID | Term |
|---|---|
| D006473 | Postpartum Hemorrhage |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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Serum and plasma
| D011644 | Puerperal Disorders |
| D014592 | Uterine Hemorrhage |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |