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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Single incision laparoscopic surgery | Experimental | Transumbilical single incision laparoscopic surgery will be performed for patients in this group.And addition of only one trocar through the stoma for drainage tube is allowed. |
|
| Conventional laparoscopic surgery | Active Comparator | Conventional laparoscopic surgery for colorectal cancer will be performed for patients in this group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Single incision laparoscopic surgery | Procedure |
|
| |
| Measure | Description | Time Frame |
|---|---|---|
| Early morbidity rate | The early morbidity rate is defined as the event observed during operation and within 30 days after surgery, | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Operative outcomes | Operative time, estimated blood loss and incision length are recorded. | intraoperative |
| Pathological outecomes | Tumor size, length of proximal and distal margin and lymph nodes harvested are used to assess oncological resection. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guoxin Li, M.D., PH.D. | Contact | +86-138-0277-1450 | gzliguoxin@163.com | |
| Yanan Wang, M.D. | Contact | +86-150-1875-3181 | wyn8116@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Guoxin Li, M.D., PH.D. | Nanfang Hospital, Southern Medical University, China | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nanfang Hospital, Southern Medical University | Recruiting | Guangzhou | Guangdong | 510-515 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19966617 | Background | Bucher P, Pugin F, Morel P. Single-port access laparoscopic radical left colectomy in humans. Dis Colon Rectum. 2009 Oct;52(10):1797-801. doi: 10.1007/DCR.0b013e3181b551ce. | |
| 20734083 | Background | Gash KJ, Goede AC, Chambers W, Greenslade GL, Dixon AR. Laparoendoscopic single-site surgery is feasible in complex colorectal resections and could enable day case colectomy. Surg Endosc. 2011 Mar;25(3):835-40. doi: 10.1007/s00464-010-1275-8. Epub 2010 Aug 24. |
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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| Conventional laparoscopic surgery |
| Procedure |
|
|
| 5 days |
| Postoperative recovery course | Time to first ambulation, flatus, liquid diet, soft diet, and duration of hospital stay are used to assess the postoperative recoverty course. | 14 days |
| Pain score | Postoperative pain is recorded using the visual analog scale (VAS) pain score tool on postoperative day 1, 2, 3 and the day of discharge. | 14 days |
| Cosmetic assessment | Cosmetic assessment is perform using body image scale and cosmetic scale. | 14 days |
| 3-year disease free survival rate | 36 months |
| 5-year overall survival rate | 60 months |
| Inflammatory and immune response | 7 days |
| 22991135 | Background | Lim SW, Kim HJ, Kim CH, Huh JW, Kim YJ, Kim HR. Umbilical incision laparoscopic colectomy with one additional port for colorectal cancer. Tech Coloproctol. 2013 Apr;17(2):193-9. doi: 10.1007/s10151-012-0900-z. Epub 2012 Sep 19. |
| 23238505 | Background | Hirano Y, Hattori M, Douden K, Shimizu S, Sato Y, Maeda K, Hashizume Y. Single-incision plus one port laparoscopic anterior resection for rectal cancer as a reduced port surgery. Scand J Surg. 2012;101(4):283-6. doi: 10.1177/145749691210100411. |
| 38062421 | Derived | Zhang X, Yuan H, Tan Z, Li G, Xu Z, Zhou J, Fu J, Wu M, Xi J, Wang Y. Long-term outcomes of single-incision plus one-port laparoscopic surgery versus conventional laparoscopic surgery for rectosigmoid cancer: a randomized controlled trial. BMC Cancer. 2023 Dec 7;23(1):1204. doi: 10.1186/s12885-023-11500-2. |
| 30006846 | Derived | Wang Y, Deng H, Mou T, Li J, Liu H, Zhou H, Li G. Short-term outcomes of single-incision plus one-port laparoscopic versus conventional laparoscopic surgery for rectosigmoid cancer: a randomized controlled trial. Surg Endosc. 2019 Mar;33(3):840-848. doi: 10.1007/s00464-018-6350-6. Epub 2018 Jul 13. |
| 26620555 | Derived | Wang Y, Liu R, Zhang Z, Xue Q, Yan J, Yu J, Liu H, Zhao L, Mou T, Deng H, Li G. A safety study of transumbilical single incision versus conventional laparoscopic surgery for colorectal cancer: study protocol for a randomized controlled trial. Trials. 2015 Nov 30;16:539. doi: 10.1186/s13063-015-1067-5. |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |