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This prospective study aimed to validate a new prognostic approach of endothelial progenitor cells associated biomarkers in patients with acute coronary syndromes . Recruitment is made prospectively by two centers of Inter -region South Mediterranean,
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| study of PEC markers and chemokines/ chemokine recep | Other | blood sample for dosage and study of PEC markers and chemokines/ chemokine receptors |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blood sample | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| evaluate the value of circulating endothelial progenitor cells quantification in the initial phase of ACS in predicting the occurrence of a major cardiovascular event (ECVM ) at 1 year. | one year |
| Measure | Description | Time Frame |
|---|---|---|
| determine the technical characteristics (sensitivity and specificity) and predictive value of the number of PEC | one day , one month , one year |
| Measure | Description | Time Frame |
|---|---|---|
| determine the technical characteristics (sensitivity and specificity) and performance (technical and predictive) of chemokines / receptors expression in the occurrence of ECVM | one day, one month ,one year | |
| Determine the above performance in the subgroup of patients defined as incompletely revascularized (at least a residual stenosis < 70%) |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| assistance Publique Hopitaux de Marseille | Marseille | 13015 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8962261 | Result | Buelens C, De Groote D, Goldman M, Willems F. Differential effects of interleukin-10 on the production of interleukin-12 and interleukin-8 by human dendritic cells generated from peripheral blood. Transplant Proc. 1996 Dec;28(6):3255-6. No abstract available. |
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| ID | Term |
|---|---|
| D054058 | Acute Coronary Syndrome |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| one year |
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |