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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A00216-41 | Other Identifier | ANSM |
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The bacterial diversity of HIV patients digestive microbiota seropositive is poorly understood, it remains to be defined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HIV-1 patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physiopathology study | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion and type of OTU (Operational Taxonomic Unit) assigned to the rank of phylum genus and species of bacteria in the intestinal microbiota of HIV-1 seropositive patients. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion and OTU types in the gastrointestinal microbiota of HIV-1 seropositive patients compared to the general population | Baseline | |
| Proportion and OTU types in the gastrointestinal microbiota of HIV-1 seropositive patients based on CD4, viral load, the Elite controller status, antiretroviral and antibiotic treatment and the existence of invasive bacterial infections. |
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Inclusion Criteria:
Exclusion Criteria:
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HIV-1 seropositive patients
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| Name | Affiliation | Role |
|---|---|---|
| Didier Raoult, MD | IHU Méditerranée infection | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Henri Mondor | Créteil | 94010 | France | |||
| Service de Médecine Interne et Immunologie Clinique |
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Stool sample
| Baseline |
| Proportion and OTU types in the gastrointestinal microbiota of HIV-1 seropositive patients based on inflammation parameters (IL-6, TNF-a, IP-10), CRPus, CD14 and integrity of the epithelial barrier (I-FABP). | Baseline |
| Transcriptomic analysis in the groups that present differences in the microbiota and analysis of lymphocyte populations Th17 and Treg. | Baseline |
| Le Kremlin-Bicêtre |
| 94275 |
| France |
| IHU Méditerranée Infection; Hôpital Nord, AP-HM | Marseille | 13005 | France |
| Service de maladies Infectieuses | Marseille | 13005 | France |