Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control. Comparison of epidural and femoral nerve block is lacking, furthermore effect on chronic pain is unclear. The investigators aimed to compare the effects of epidural and femoral block on acute and chronic postoperative pain.
Background and aim Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control. Comparison of epidural and femoral nerve block is lacking, furthermore effect on chronic pain is unclear. The investigators aimed to compare the effects of epidural and femoral block on acute and chronic postoperative pain.
Methods The study was of randomized, prospective, and double-blind design and was conducted with 80 patients who had undergone total knee prosthetic replacement surgery with the insertion of a femoral nerve block or epidural block catheter to initiate postoperative analgesia. One-sided spinal anesthesia was performed in all the patients. Postoperative pain control was achieved with the administration via catheter using bupivacaine for patient-controlled analgesia. Acute postoperative pain was evaluated in the first 24 hours and chronic postoperative pain in the 1st and 3rd months following surgery. The anxiety/depression scale was used to assess anxiety and depression, the SF 12 test was used to evaluate quality of life, and the DN4 test was employed at patient visits at the 1st and 3rd months.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| epidural block | Experimental | Visual anlogue score vas used to evaluate pain. The anxiety/depression scale (HAD) was used to assess anxiety and depression. The SF 12 test (SHORT FORM 12) was used to evaluate quality of life. The DN4 test was used to evaluate neuropathic pain. |
|
| femoral block | Active Comparator | Visual anlogue score vas used to evaluate pain. The anxiety/depression scale (HAD) was used to assess anxiety and depression. The SF 12 test (SHORT FORM 12) was used to evaluate quality of life. The DN4 test was used to evaluate neuropathic pain. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DN4 test | Other | The DN4 test was used to evaluate neuropathic pain. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Persistent surgical pain after total knee arthroplasty assessed by VAS scale | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| The anxiety and depression was evaluated with Hospital anxiety and depression scale. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life was evaluated with SF 12 test. | 3 months | |
| Neuropathic pain was evaluated with DN4 test. | 3 months. |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Sinem Sari, Assistant Prof | Adnan Menderes University Medical Faculty Anesthesiology and Reanimation Department | Study Chair |
| Fatma Şengül, MD | Antalya Education and Research Hospital, Anesthesiology and Reanimation Department, Antalya; Turkey | Principal Investigator |
| FabrizioGalimberti Galimberti, Medical Student | Cleveland ClinicLernerCollege of Medicine, Cleveland, Ohio | Principal Investigator |
| Bilge Karslı, Prof | Antalya Education and Research Hospital, Anesthesiology and Reanimation Department, Antalya; Turkey | Principal Investigator |
| Alparslan Turan, Associate Prof | Department of Outcomes Research, Cleveland Clinic | Principal Investigator |
| Murat Bakıs, Assistant Prof | Adnan Menderes University Medical Faculty, Anesthesiology and Reanimation Department, Aydin; Turkey | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Adnan Menderes University Medical Faculty, Anesthesiology and Reanimation Department | Aydin | 09100 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23142441 | Result | Chan EY, Fransen M, Sathappan S, Chua NH, Chan YH, Chua N. Comparing the analgesia effects of single-injection and continuous femoral nerve blocks with patient controlled analgesia after total knee arthroplasty. J Arthroplasty. 2013 Apr;28(4):608-13. doi: 10.1016/j.arth.2012.06.039. Epub 2012 Nov 8. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
Not provided
Not provided
| ID | Term |
|---|---|
| D000767 | Anesthesia, Epidural |
| ID | Term |
|---|---|
| D000765 | Anesthesia, Conduction |
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| The SF 12 test | Other | The SF 12 test (SHORT FORM 12) was used to evaluate quality of life. |
|
|
| HAD scale | Other | The anxiety/depression scale (HAD) was used to assess anxiety and depression. |
|
|
| Visual analogue score | Other | Visual analogue score vas used to evaluate pain. |
|
|
| femoral block | Procedure |
|
| epidural block | Procedure |
|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |