IORT-Boost-Study, Prospective Observational Study for Intraoperative Radiotherapy of the Breast as a Boost

Prospective Observational Study for Intraoperative Radiotherapy (IORT) of the Breast as a Boost

In this study the investigators observe the investigation, whether the new method for Boost-Irradiation with the Intrabeam Device of Zeiss Germany influences local recurrence, acute and late effects of Radiotherapy, overall survival, quality of life and cosmesis.

Inclusion Criteria:

• women with histologically proven unifocal ductal-invasive or other histology of breast-cancer, size of tumor < or = 3.5 cm
• written informed consent
• ability to cooperate
• full legal capability

Exclusion Criteria:

• missing written informed consent
• lack of compliance