Assessment of the Effect of Atorvastatin on Prevention of CIN in Patients Undergoing Coronary Angiography

Atorvastatin and Prevention of Contrast Induced Nephropathy Following Coronary Angiography

As the effect of statin use before the angiography to prevent contrast induced nephropathy (CIN) is not well-known, the aim of the current study is to assess the effect of atorvastatin on prevention of CIN in patients undergoing coronary angiography.

Inclusion Criteria:

• having chronic stable angina who were referred for coronary angiography
• non-pregnant female subjects
• no history of diabetes mellitus
• no history of renal failure
• no history of single kidney
• no history of cardiogenic shock
• no history of unstable angina
• no history of myocardial infarction
• no history of hypersensitivity to statins
• no history of previous intravascular contrast injection during one month before admission

Exclusion Criteria:

• glomerular filtration rate (GFR) <60
• cardiogenic shock