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The objectives of this study is to assess the characteristics and frequency of adenovirus conjunctivitis in a population of male and female patients from one year of age who present signs and symptoms of acute conjunctivitis.
Epidemiological, prospective, open, multicentric trial in patients suffering from acute conjunctivitis who will undergo a rapid diagnostic test for adenoviral conjunctivitis at the time of their visit to the ophthalmologist office, at the emergency room or during hospitalization. This epidemiological study will include approximately 500 patients in the United Kingdom. The planned duration of the study is one year from the first patient visit to the last patient visit.
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| Measure | Description | Time Frame |
|---|---|---|
| Frequency of patients with adenovirus conjunctivitis | The percentage of patients with adenovirus conjunctivitis documented by a positive AdenoPlus® test over the tested population of male and female patients who present signs and symptoms of acute conjunctivitis. | During the visit to the ophthalmologist before and just after the AdenoPlus® test done on the same day (one visit) |
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| Measure | Description | Time Frame |
|---|---|---|
| Seasonality and geographic repartition observed. | The number of patients with adenovirus conjunctivitis who visited the ophthalmologist in spring, summer, autumn and winter and their geographic area (e.g. by hospital, by area). | During the visit to the ophthalmologist before and just after the AdenoPlus® test done on the same day (one visit) |
Inclusion Criteria:
Exclusion Criteria:
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Any female and male patients from one year of age with signs and symptoms of acute conjunctivitis either seen during ophthalmology consultations or who are in the emergency room or hospitalized, can be enrolled in the study
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| Name | Affiliation | Role |
|---|---|---|
| Rakesh Jayaswal | Portsmouth Hospitals NHS Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Queen Alexandra Hospital | Portsmouth | United Kingdom |
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| ID | Term |
|---|---|
| D003236 | Conjunctivitis, Viral |
| ID | Term |
|---|---|
| D015828 | Eye Infections, Viral |
| D015817 | Eye Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
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| Clinical profiles of the patients |
The percentage of each eye signs and symptoms, the mean duration of the disease for both the patients with positive and negative AdenoPlus® tests, the number or follow-up visit done and the correlation between the initial diagnosis (before AdenoPlus® test results) and the final diagnosis (post AdenoPlus® test results). |
| During the visit to the ophthalmologist before and just after the AdenoPlus® test done on the same day (one visit) |
| Resource utilization during the treatment and evaluation of the costs | Estimation of resource utilized during course of treatment (use of drugs, number of visits done by the patient…), and associated costs (which would be calculated by applying unit costs to resource use). | On day 1: at least once during the single visit to the ophthalmologist and if any also during the follow-up visit(s) |
| Patient/parent absenteeism linked to this disease. | Number of days out of work and/or out of school linked to this disease. | On day 1: at least once during the single visit to the ophthalmologist and if any also during the follow-up visit(s) |
| Safety assessment | Number of adverse incidents (AIs) and events that are of significant (SEs) reported to Nicox | On day 1: at least once during the single visit to the ophthalmologist and if any also during the follow-up visit(s) |
| D003231 |
| Conjunctivitis |
| D003229 | Conjunctival Diseases |
| D005128 | Eye Diseases |