Weight Loss as Treatment in Heart Disease

Intentional Weight Loss as Treatment in Obese Patients With Ischaemic Heart Disease

30 obese moderate-to-severe heart failure patients will be randomized to intervention or control in groups of 5-10 subjects.

All will receive dietetic advice according to randomization and according to the European Heart Association.

Intervention subjects will initiate with 8 weeks low energy diet, 800-1000 kcal/d by formula diet and subsequent four weeks reintroduction to regular foods supplying 1200 kcal/d substituting two daily meals with formula meal replacement.

Control subjects are advised to follow the Nordic Nutrition Recommendations.

Patients will be monitored by blood sampling and assessed by change in physical performance.

Inclusion Criteria:

• bmi >30
• heart failure, moderate to severe, new york heart association II og III
• stable disease
• age >18 years
• out-patients
• perform a six minutes walk test
• given consent

Exclusion Criteria:

• unstable disease
• insulin treated diabetes
• pregnancy or lactating
• unstable weight past 6 months (+- 10 kg)
• planned procedures in the time of intervention