This study is to evaluate the performance of Hemospray for the teatment of nonvariceal lower gastrointestinal bleeding.

Inclusion Criteria:

• Patient in which Hemospray is used to treat an endoscopically confirmed nonvariceal lower GI bleed requiring hemostasis

Exclusion Criteria:

• Less than 19 years old
• Unwilling or unable to sign and date the informed consent
• Pregnant, lactating or planning to become pregnant within 30 days of the procedure
• Contraindicated to undergo colonoscopy

Medical/Endoscopic Exclusion Criteria

• Actual or suspected lower GI perforation or fistula
• Bleeding originating from inflammatory bowel disease (e.g., Crohn's disease or ulcerative colitis)
• Actual or suspected ischemic colitis or infectious colitis
• Unable to visualize site of active bleeding (such as suspected diverticular bleed where source is unable to be identified)
• Unable to treat active site of bleeding (e.g., bleeding site cannot be reached by the colonoscope)

clinical sites