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| ID | Type | Description | Link |
|---|---|---|---|
| PDvsCOPD | Other Identifier | Ospedale generale di zona "Moriggia-Pelascini" |
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The aims of this study is to assess the efficacy of the crossover on balance in Parkinsonian patients and compare this results with the results of a control group of patients treated with a stabilometric platform.
Parkinson's disease (PD) is a neurodegenerative disorder characterized by different motor symptoms (rigidity, akinesia, tremor and impairment of balance and gait). Even though pharmacological treatment has changed the natural course of the disease, balance worsens over time and leads to falls. The aims of this study is to assess the efficacy of the crossover (group 1) on balance in Parkinsonian patients and compare this results with the results of a control group of patients treated with a stabilometric platform (group 2). The group 1 executed 6 days/week for a 4-weeks cycle a crossover protocol based on the first 4 level of resistance and a training which lasts at most 5 minutes. The group 2 executed 6 days/week for a 4-weeks cycle different exercises with the stabilometric platform in monopodalic and in bipodalic standing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PD patients cross-over treatment | 30 PD patients (according to Gelb et al) in Hoen&Yahr stage 3, underwent cross-over treatment with the ability to walk without any assistance with mini-mental state examination score >26. |
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| PD patients stabilometric platform | 30 PD patients (according to Gelb et al) in Hoen&Yahr stage 3, underwent stabilometric platform treatment, with the ability to walk without any assistance with mini-mental state examination score >26. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Crossover | Other | Crossover cycle |
| |
| Stabilometric Platform |
| Measure | Description | Time Frame |
|---|---|---|
| BBS | Berg Balance Scale | One month |
| Measure | Description | Time Frame |
|---|---|---|
| 6MWT | Six minutes walking test | One month |
| TUG | Time up and Go test | One month |
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Inclusion Criteria:
Exclusion Criteria:
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60 patients with PD in stage III Hoen&Yahr according to Gelb et la. with the ability to walk without any assistance and with Mini Mental State Examination (MMSE) score > 26.
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| Name | Affiliation | Role |
|---|---|---|
| Giuseppe Frazzitta, MD | Ospedale generale di Zona "Moriggia-Pelascini", Gravedona ed Uniti 22015 - CO, Italy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ospedale generale di zona "Moriggia-Pelascini" | Gravedona | Como | 22015 | Italy |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D003434 | Crossing Over, Genetic |
| ID | Term |
|---|---|
| D059765 | Homologous Recombination |
| D011995 | Recombination, Genetic |
| D055614 | Genetic Phenomena |
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| Other |
This Stabilometric plate allows to assess the balance with an objective and reliable measurement, in both standard static or dynamic unstable condition |
|
| UPDRS II | Unified Parkinson's disease Rating Scale II | One month |
| UPDRS III | Unified Parkinson's disease Rating Scale III | One month |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |