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| Name | Class |
|---|---|
| Kyambogo University | OTHER |
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Undernutrition and growth restriction due to poor diet and inadequate nutrient intake continues to be a global challenge, particularly in the developing countries including Uganda. The etiology of inadequate nutrient supply to infants may relate to lack of resources or knowledge or a combination of both. Poor nutrient intake and impaired growth may affect brain and cognitive development.
This study aims to evaluate nutrient intake, growth and cognitive function among children between 6 and 36 months living in the fertile Kabale and Kisoro region in south-western Uganda. The investigators hypothesize that nutrition education to mothers can bring about improved dietary intake and nutritional status among children aged 6-36 months.
A follow-up study was conducted during the period January - July 2022.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | No Intervention | ||
| intervention | Experimental | Nutritional intervention (nutrition education) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Improving nutrition knowledge among mothers | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in the prevalence of stunting (<-2 SD of the WHO, 2006 growth reference standards) | The investigators will measure the change in stunting between the three indicated time points. | 6-8, 12-16, 20-24 (main outcome time point), 36 months, 7-10 years |
| Measure | Description | Time Frame |
|---|---|---|
| Change in mean weight-for-age z-score | The investigators will measure the change in mean weight for age z-score between the three indicated time periods. | 6-8, 12-16 and 20-24, 36 months, 7-10 years |
| Change in mean weight-for-height z-score |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kyambogo University | Kampala | Uganda |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34461584 | Derived | Atukunda P, Ngari M, Chen X, Westerberg AC, Iversen PO, Muhoozi G. Longitudinal assessments of child growth: A six-year follow-up of a cluster-randomized maternal education trial. Clin Nutr. 2021 Sep;40(9):5106-5113. doi: 10.1016/j.clnu.2021.08.007. Epub 2021 Aug 20. | |
| 33706831 | Derived | Kakwangire P, Moss C, Matovu N, Atukunda P, Westerberg AC, Iversen PO, Muhoozi G. The association between dietary diversity and development among children under 24 months in rural Uganda: analysis of a cluster-randomised maternal education trial. Public Health Nutr. 2021 Sep;24(13):4286-4296. doi: 10.1017/S136898002100077X. Epub 2021 Mar 12. |
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| ID | Term |
|---|---|
| D007228 | Infant Nutrition Disorders |
| ID | Term |
|---|---|
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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The investigators will measure the change in mean weight for height z-score between the three indicated time periods.
| 6-8, 12-16, 20-24, 36 months, 7-10 years |
| Change in mean Mid Upper Arm Circumference (MUAC) z-score | The investigators will measure the change in MUAC between the three indicated time periods. | 6-8, 12-16, 20-24, 36 months, 7-10 years |
| Change in mean diet diversification score (DDS) | The investigators will measure the change in DDS between the three indicated time periods. | 6-8, 12-16, 20-24, 36 months |
| Change in Ages and Stages Questionnaire Scores (AQS) | The investigators will measure the change in AQS between the three indicated time periods. | 6-8, 12-16, 20-24, 36 months |
| Change in The Kaufman Assessment Battery for Children (2nd ed.; KABC-II) and the Test of Variable of Attention (TOVA) | The investigators will measure the change in the scores of these tests at indicated time periods. | 7-10 years |
| Change in Bayley Child Development test 3 ed. | The investigators will measure the change in Bayley Child Development test 3 ed. between the three indicated time periods. | 6-8, 12-16, 20-24, 36 months |
| Change in gut microbiota | Fecal samples will be collected and the investigators will measure the change in gut microbiota between the three indicated time periods. | 20-24, 36 months, 7-10 years |
| Change in oral microbiota | Saliva samples will be collected and the investigators will measure the change in oral microbiota at indicated time periods. | 36 months, 7-10 years |
| Change in Mullens test | The investigators will measure the change in Mullens test between the two groups after 36 months. | 36 months |
| Change in Becks Depression Inventory II questionnaire to determine the maternal self-reported depression symptoms | The investigators will measure the change in this test between the two groups at indicated time periods | 7-10 years |
| Change in the Center for Epidemiological Studies Depression Scale questionnaires to determine the maternal self-reported depression symptoms | The investigators will measure the change in this test between the two groups at indicated time periods | 7-10 years |
| Oral health | The investigators will assay caries using photographs | 7-10 years |
| 32654677 | Derived | Atukunda P, Muhoozi GK, Diep LM, Berg JP, Westerberg AC, Iversen PO. The association of urine markers of iodine intake with development and growth among children in rural Uganda: a secondary analysis of a randomised education trial. Public Health Nutr. 2021 Aug;24(12):3730-3739. doi: 10.1017/S1368980020001603. Epub 2020 Jul 13. |
| 31131103 | Derived | Atukunda P, Muhoozi GKM, van den Broek TJ, Kort R, Diep LM, Kaaya AN, Iversen PO, Westerberg AC. Child development, growth and microbiota: follow-up of a randomized education trial in Uganda. J Glob Health. 2019 Jun;9(1):010431. doi: 10.7189/jogh.09.010431. |
| 28925580 | Derived | Muhoozi GKM, Atukunda P, Diep LM, Mwadime R, Kaaya AN, Skaare AB, Willumsen T, Westerberg AC, Iversen PO. Nutrition, hygiene, and stimulation education to improve growth, cognitive, language, and motor development among infants in Uganda: A cluster-randomized trial. Matern Child Nutr. 2018 Apr;14(2):e12527. doi: 10.1111/mcn.12527. Epub 2017 Sep 19. |