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The purpose of this study is to assess whether radiographic osteoarthritis severity (OA; Kellgren-Lawrence scale) is associated with self-reported improvement in pain after non-surgical treatments (physiotherapy, pain killers, injection, other treatments).
The hypothesis is that radiographic OA severity is inversely associated with self-reported improvement.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non-surgical treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Paracetamol and nonsteroidal antiinflammatory drug (NSAID) | Drug |
| ||
| Physiotherapy |
| Measure | Description | Time Frame |
|---|---|---|
| Self-reported improvement | Assessed using the question: Has your pain improved? Response categories: pain free; better; unchanged; worse | 2-5 years after consulting orthopedic surgeon |
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Inclusion Criteria:
Exclusion Criteria:
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2200 patients with knee osteoarthritis not eligible for at total knee arthroplasty
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| Name | Affiliation | Role |
|---|---|---|
| Michael Rathleff, MSc | Department of Occupational Therapy and Physiotherapy, Aalborg University Hospital, Denmark. | Study Chair |
| Mikkel M Andersen, MSc | Department of Mathematical Sciences, Aalborg University | Study Chair |
| Ole Simonsen, MD, DMSc | Department of Orthopedic Surgery | Principal Investigator |
| Christina A Derosche, BSc | Department of Orthopedic Surgery | Study Chair |
| Signe B Pedersen | Department of Orthopedic Surgery | Study Chair |
| Søren T Skou, MSc | Orthopedic Surgery Research Unit + Department of Health Science and Technology, Aalborg University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Orthopedic Surgery | Aalborg | 9000 | Denmark |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D000082 | Acetaminophen |
| D000894 | Anti-Inflammatory Agents, Non-Steroidal |
| D026741 | Physical Therapy Modalities |
| D003348 | Cortisone |
| C105840 | Bro protein, Drosophila |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
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| Other |
|
| Cortisone Injection | Drug |
|
| Others | Other |
|
| D012216 |
| Rheumatic Diseases |
| Aniline Compounds |
| D000588 | Amines |
| D018712 | Analgesics, Non-Narcotic |
| D000700 | Analgesics |
| D018689 | Sensory System Agents |
| D018373 | Peripheral Nervous System Agents |
| D045505 | Physiological Effects of Drugs |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D000893 | Anti-Inflammatory Agents |
| D045506 | Therapeutic Uses |
| D018501 | Antirheumatic Agents |
| D013812 | Therapeutics |
| D012046 | Rehabilitation |
| D011283 | Pregnenes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D015065 | 17-Hydroxycorticosteroids |
| D006889 | Hydroxycorticosteroids |
| D000305 | Adrenal Cortex Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |