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This study investigates nutrition bar consumption and possible impact on self-reported ratings of hunger and fullness compared to a control.
Participant eligibility will be screened at visit 1. Test days will commence at 8 to 10 a.m. and visits two to four will be spaced four days apart. On visit days participants consume a nutrition bar; satiety and hunger ratings, blood samples are collected simultaneously over a three hour period. After completion, participants will complete gastrointestinal (GI) tolerability as well as Palatability and Adverse Events questionnaires.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nutrition bar | Placebo Comparator | 50 g nutrition bar |
|
| Nutrition Bar 1 | Experimental | 50 g nutrition bar with additional 2 g of milk-based nutrient |
|
| Nutrition bar 2 | Experimental | 50 g nutrition bar with additional 3 g of milk-based nutrient |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nutrition Bar | Other | Intervention involves consumption of one nutrition bar of approximately 50 g in the beginning of each visit of the crossover sequence |
|
| Measure | Description | Time Frame |
|---|---|---|
| self-reported hunger and fullness rating | change in self-reported hunger or fullness compared to placebo | 3 hour period after consumption of study product, on 3 occasions |
| Measure | Description | Time Frame |
|---|---|---|
| blood sample analytes | change in analyte concentrations compared to placebo | 3 hour period after consumption of study product, on 3 occasions |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Douglas Bolster, PhD | PepsiCo, Inc. | Principal Investigator |
| Laura Harkness, PhD | PepsiCo, Inc. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Glycemic Index Laboratories | Toronto | Ontario | M5C 2N8 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29897544 | Derived | Bolster DR, Rahn M, Kamil AG, Bristol LT, Goltz SR, Leidy HJ, Blaze Mt M, Nunez MA, Guo E, Wang J, Harkness LS. Consuming Lower-Protein Nutrition Bars with Added Leucine Elicits Postprandial Changes in Appetite Sensations in Healthy Women. J Nutr. 2018 May 1;148(5):693-701. doi: 10.1093/jn/nxy023. |
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