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| ID | Type | Description | Link |
|---|---|---|---|
| 430519 | Other Identifier | University of California, Davis |
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Study was withdrawn because the university wanted to bill study patients for use of the laser.
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The aim of this study is to compare the efficacy of various treatment options for eliminating nasal telangiectasias. The study will compare the outcome of treating nasal telangiectasias with the following; no treatment (control site), alexandrite laser, pulsed dye laser, combination pulsed dye laser and Nd:YAG 1064nm multiplex laser system and electrosurgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pulsed Dye Laser | Active Comparator | Subjects with multiple nose telangiectasias will be enrolled. One nose telangiectasia (of 5) will be treated with pulsed dye laser. |
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| Long Pulsed Alexandrite Laser | Active Comparator | Subjects with multiple nose telangiectasias will be enrolled. One nose telangiectasia (of 5) will be treated with long pulsed alexandrite laser. |
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| Pulsed Dye Laser Plus Nd:YAG Laser | Active Comparator | Subjects with multiple nose telangiectasias will be enrolled. One nose telangiectasia (of 5) will be treated with pulsed dye laser plus Nd:YAG laser. |
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| Electrodesiccation | Active Comparator | Subjects with multiple nose telangiectasias will be enrolled. One nose telangiectasia (of 5) will be treated with electrodesiccation. |
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| No Treatment | No Intervention | Subjects with multiple nose telangiectasias will be enrolled. One nose telangiectasia (of 5) will receive no treatment. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pulsed Dye Laser | Device | Pulsed dye laser treatments will be performed with a 595 nanometer wavelength, 20 millisecond pulse duration, at 10 Joules/cm2, with a 10 millimeter spot size. |
| Measure | Description | Time Frame |
|---|---|---|
| Reduction of Area of Nasal Telangiectasias by Laser Therapy Vs Electrosurgery | The study will measure the changes in length and width (area) of nasal telangiectasias before and after treatment with the following: no treatment (control site), alexandrite laser, pulsed dye laser, combination pulsed dye laser and Nd:YAG 1064nm multiplex laser system and electrosurgery. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of Cosmetic Improvement | Percent perceived improvement for nasal vessels by the patient via questionnaire. | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Daniel Eisen, M.D. | University of California, Davis | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California-Davis, Department of Dermatology | Sacramento | California | 95816 | United States |
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| Label | URL |
|---|---|
| University of California-Davis Department of Dermatology Clinical Research | View source |
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| ID | Term |
|---|---|
| D013684 | Telangiectasis |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D054025 | Lasers, Dye |
| ID | Term |
|---|---|
| D007834 | Lasers |
| D055096 | Optical Devices |
| D004864 | Equipment and Supplies |
| D055618 | Radiation Equipment and Supplies |
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| Long Pulsed Alexandrite Laser | Device | Alexandrite laser will be used with a 755 nanometer wavelength, 40 millisecond pulse duration, at 88Joules/cm2, with a 6 millimeter spot size. |
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| Pulsed Dye Laser Plus Nd:YAG Laser | Device | The Cynergy with MultiPlex will be used with a multiplex mode system with a pulse dye laser at 585 nanometer wavelength, 20 milliseconds pulse duration, at 7 Joules/cm2 with a 7 millimeter spot size, with a short delay, followed by a Nd:YAG 1064 nanometer wavelength, 20 millisecond pulse duration, at 50 Joules/cm2 with a 7 millimeter spot size. |
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| Electrodesiccation | Procedure | A curette is used to scrape off the cancer down to the dermis. The scraping is then paused while an electrosurgical device like a hyfrecator is used next. Electrodesiccation is performed over the raw surgical ulcer to denature a layer of the dermis and the curette is used again over the surgical ulcer to remove denatured dermis down to living tissue. |
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