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| ID | Type | Description | Link |
|---|---|---|---|
| Tumorregister Pankreaskarzinom | Other Identifier | iOMEDICO |
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The registry aims to collect and analyse information on the antineoplastic treatment of patients with unresectable locally advanced or metastatic pancreatic cancer, treated in palliative intention (cohort 1) and patients with localized, resectable pancreatic cancer treated in neo-adjuvant or adjuvant intention (cohort 2) in daily routine practice in Germany. The registry will follow up patients for two years. It will identify common sequences of treatments used as well as changes in the treatment of the disease. Health-related quality of life will be analysed during the course of the treatment (PanLife). Based on the available data a prognostic score will be developed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cohort 1 | 2,200 patients with unresectable locally advanced or metastatic pancreatic cancer, treated in palliative intention | ||
| Cohort 2 | 125 patients with localized, resectable pancreatic cancer treated in neo-adjuvant or adjuvant intention |
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| Measure | Description | Time Frame |
|---|---|---|
| Treatment reality in Germany | description of treatments selected for patients per line of therapy over the course of the project | over 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with pancreatic cancer undergoing antineoplastic treatment.
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| Name | Affiliation | Role |
|---|---|---|
| Susanna Hegewisch-Becker, Prof. MD | Outpatient Clinic, Hamburg | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| iOMEDICO | Freiburg im Breisgau | Baden-Wurttemberg | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30006989 | Background | Hegewisch-Becker S, Aldaoud A, Wolf T, Krammer-Steiner B, Linde H, Scheiner-Sparna R, Hamm D, Janicke M, Marschner N; TPK-Group (Tumour Registry Pancreatic Cancer). Results from the prospective German TPK clinical cohort study: Treatment algorithms and survival of 1,174 patients with locally advanced, inoperable, or metastatic pancreatic ductal adenocarcinoma. Int J Cancer. 2019 Mar 1;144(5):981-990. doi: 10.1002/ijc.31751. Epub 2018 Oct 3. | |
| 36053905 |
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| ID | Term |
|---|---|
| D010190 | Pancreatic Neoplasms |
| D009369 | Neoplasms |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004701 | Endocrine Gland Neoplasms |
| D004066 | Digestive System Diseases |
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| Background |
| Marschner N, Hegewisch-Becker S, Reiser M, von der Heyde E, Bertram M, Hollerbach SH, Kreher S, Wolf T, Binninger A, Chiabudini M, Kaiser-Osterhues A, Janicke M; TPK-Group (Tumour Registry Pancreatic Cancer). FOLFIRINOX or gemcitabine/nab-paclitaxel in advanced pancreatic adenocarcinoma: A novel validated prognostic score to facilitate treatment decision-making in real-world. Int J Cancer. 2023 Feb 1;152(3):458-469. doi: 10.1002/ijc.34271. Epub 2022 Sep 22. |
| 38956837 | Background | Marschner N, Haug N, Hegewisch-Becker S, Reiser M, Dorfel S, Lerchenmuller C, Linde H, Wolf T, Hof A, Kaiser-Osterhues A, Potthoff K, Janicke M; TPK-Group (Tumour Registry Pancreatic Cancer). Head-to-head comparison of treatment sequences in advanced pancreatic cancer-Real-world data from the prospective German TPK clinical cohort study. Int J Cancer. 2024 Nov 1;155(9):1629-1640. doi: 10.1002/ijc.35071. Epub 2024 Jul 2. |
| D010182 | Pancreatic Diseases |
| D004700 | Endocrine System Diseases |