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| Name | Class |
|---|---|
| Sahlgrenska University Hospital | OTHER |
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Patients with newly diagnosed achalasia have been submitted to either treatment with pneumatic dilatation or surgical myotomy. Minimal follow up five years.
Patients with newly diagnosed achalasia have been submitted to either treatment with pneumatic dilatation or surgical myotomy. Minimal follow up five years.
During follow up patients have been interviewed with regular intervals, by use validated questionnaires. The level of symptom control has been assessed as well as the scoring cumulative incidence of treatment failures.
Health Related Quality of Life (HRQL) has been regularly checked.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pneumatic dilatation | Experimental | Repetitive pneumatic dilatation as the initial treatment followed by repetitive dilatation in case of dysphagia recurrence. |
|
| Surgical myotomy | Active Comparator | Laparoscopic myotomy and subsequent follow up. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pneumatic dilatation | Procedure |
| ||
| Laparoscopic myotomy |
| Measure | Description | Time Frame |
|---|---|---|
| Treatment failures | Treatment failure is defined as a Composite variabel containing a number of different Clinically relevant outcomes. | At least five years after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Dysphagia scoring | Dysphagia score according to standardized, validated scoring system. | At least five years after intervention |
| Health Related Quality of Life | Universally adopted and validated instruments are used. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lars Lundell, Professor | Karolinska University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sahlgrenska University Hospital | Gothenburg | 41132 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25409838 | Derived | Persson J, Johnsson E, Kostic S, Lundell L, Smedh U. Treatment of achalasia with laparoscopic myotomy or pneumatic dilatation: long-term results of a prospective, randomized study. World J Surg. 2015 Mar;39(3):713-20. doi: 10.1007/s00268-014-2869-4. |
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| ID | Term |
|---|---|
| D004931 | Esophageal Achalasia |
| ID | Term |
|---|---|
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
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| ID | Term |
|---|---|
| D000074434 | Heller Myotomy |
| ID | Term |
|---|---|
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D000074432 | Sphincterotomy |
| D000074433 | Myotomy |
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| At least five years after intervention. |
| Direct medical costs. | Charges for the average hospital in respective countries. | At least five years after intervention. |
| D004066 | Digestive System Diseases |