The aim of this study protocol will be to compare the technique of intracorporeal morcellation using reusable electronic device (standard technique) with a technique of removal "protected" by endobag and extracorporeal myoma morcellation with cold scissors and scalpel blade or with power morcellator used inside the bag itself.

Inclusion Criteria:

• Patients undergoing laparoscopy for uterine myomas with international guidelines surgical indications
• Presence of at least one uterine myoma larger than 4 cm
• Aged between 18 and 40 years

Exclusion Criteria:

• Presence of uterine neoformations suspicious for malignancy
• Medical major disorders associated
• Acute or chronic psychiatric disorders
• Ascertained Premenstrual syndrome
• Use of drugs that can affect cognitive ability or state of consciousness and alertness during the last six months prior to enrollment
• Presence of calcified fibroids ultrasound examination
• Presence of adnexal lesions
• Detection of a pattern of endometrial hyperplasia with atypia determined in the course endometrial biopsy performed for abnormal uterine bleeding
• Abnormal PAP test
• Positive Pregnancy Test
• Previous use of laparoscopic surgery increased