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The research is to study the effectiveness and safety of combined lumbar plexus and sciatic nerve block by the guide of peripheral nerve stimulator (PNS) in unilateral knee replacement.There have be some papers which supported that combined lumbar plexus and sciatic nerve block may be more suitable for the old men.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nerve block | Experimental | Patients in this group were assigned to receive lumbar plexus block and sciatic nerve block guided by PNS. |
|
| combined spinal and epidural anesthesia | Placebo Comparator | Combined spinal and epidural anesthesia were performed in patients of this group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nerve block | Procedure | Patients in this group were assigned to receive lumbar plexus block and sciatic nerve block both using 0.33% ropivacaine 30ml guided by PNS |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maintenance time of sensory and motor nerve block | from the end of injection of local anesthetic drug up to 24h after operation | up to 24h after operation |
| Measure | Description | Time Frame |
|---|---|---|
| The change of hemodynamics | the changes of SBP and DBP at 0, 5, 10, 20, 30, 60 min after injection | 0, 5, 10, 20, 30, 60 min after injection |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guangzhou Military Region General Hospital, Department of Anesthesiology | Guangzhou | Guangdong | 510010 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8069988 | Result | Farny J, Girard M, Drolet P. Posterior approach to the lumbar plexus combined with a sciatic nerve block using lidocaine. Can J Anaesth. 1994 Jun;41(6):486-91. doi: 10.1007/BF03011542. | |
| 21156977 | Result | de Leeuw MA, Slagt C, Hoeksema M, Zuurmond WW, Perez RS. Hemodynamic changes during a combined psoas compartment-sciatic nerve block for elective orthopedic surgery. Anesth Analg. 2011 Mar;112(3):719-24. doi: 10.1213/ANE.0b013e318206bc30. Epub 2010 Dec 14. |
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| ID | Term |
|---|---|
| D009407 | Nerve Block |
| D000767 | Anesthesia, Epidural |
| D000077212 | Ropivacaine |
| D002045 | Bupivacaine |
| ID | Term |
|---|---|
| D000765 | Anesthesia, Conduction |
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
| D003714 | Denervation |
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| Combined spinal and epidural anesthesia | Procedure | Combined spinal and epidural anesthesia were performed in patients of this group with 0.5% hyperbaric bupivacaine 8~10mg at L2-3 or L3-4. |
|
| Ropivacaine | Drug | Patients will be assigned to receive lumbar plexus block and sciatic nerve block both using 0.33% ropivacain 30ml guided by PNS. |
|
|
| Bupivacaine | Drug | Combined spinal and epidural anesthesia will be performed in patients with 0.5% hyperbaric bupivacaine 8~10mg. |
|
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| D019635 |
| Neurosurgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |