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The purpose of this research study is to investigate whether minimizing interference improves memory in multiple sclerosis.
The ability to form new long-lasting memories is important for successful independent living and a high quality of life. Roughly half of the individuals diagnosed with Multiple Sclerosis (MS) have difficulty remembering new information and this is likely associated with poor acquisition of new information. There are only a limited number of studies that have investigated memory consolidation in MS. The current study will investigate the role of interference during the consolidation time period of memory formation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Unfilled interference | Experimental | Interference onset: delayed test at 540000 ms |
|
| Early interference | Experimental | Interference onset: delayed test at 0 ms |
|
| Mid interference | Experimental | Interference onset: delayed test at 360000 ms |
|
| Late interference | Experimental | Interference onset: delayed test at 180000 ms |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Interference onset | Behavioral | Temporal duration of interference onset. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Recall Proportion | 2 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kessler Foundation | West Orange | New Jersey | 07052 | United States |
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| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
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| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |