This is a study to determine the effect of four different dosing regimens of CLP in normal healthy volunteers.

Inclusion Criteria:

• Healthy volunteer is ≥ 18 years of age with BMI of 18-32
• Females could not be pregnant or breast feeding and had to be using birth control
• Must have regular bowel habits, typically producing at least 1 daily bowel movement

Exclusion Criteria:

• Screening 12-lead ECG demonstrating QTc interval >430 msec for males and >450 msec for females, or any cardiac rhythm disorder considered by the Investigator to be clinically relevant
• History or presence of gastrointestinal conditions
• Positive drug screen for substances of abuse
• Positive results for HIV, hepatitis B, or hepatitis C