Not provided
Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 1R43NS076052-01A1 | U.S. NIH Grant/Contract | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| The Cleveland Clinic | OTHER |
| National Institute of Neurological Disorders and Stroke (NINDS) | NIH |
It is often difficult to quantify and distinguish aspects of abnormal muscle tone due to neurological injury. This makes it difficult to evaluate therapies that aim to reduce the effects of abnormal muscle tone. This research study will evaluate the feasibility of a clinician worn device to capture and quantify features of spasticity and dystonia.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stroke | Ten individuals with chronic stroke and limb spasticity will be recruited. | ||
| Dystonia | Ten individuals with dystonic limbs and no spasticity will be recruited. | ||
| Cerebral Palsy | Ten individuals with Cerebral palsy with the potential for a mix of dystonic and spastic abnormal tone in their affected limbs will be recruited. | ||
| Neurologically normal | Thirty individuals without neurological injury that are age matched to the rest of the study population will be recruited. |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between clinician and device measured abnormal tone type. | Device measurements of clinician applied force relative to limb manipulation speed will be compared to conventional clinical outcome measures. For example, correlation between the slope of the force to speed profile and clinician evaluated spasticity, Ashworth score, will be calculated. | For each subject clinician and device data will be collected within a single session. Each session will occur over a maximum of two hours. Analysis of all of the subject data will be completed within 30 days of study completion. |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Sixty individuals, including individuals with and without abnormal muscle tone will be recruited for this study.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Joseph P Giuffrida, PhD | Great Lakes NeuroTechnologies Inc. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Great Lakes NeuroTechnologies | Valley View | Ohio | 44125 | United States |
Not provided
| ID | Term |
|---|---|
| D020521 | Stroke |
| D004421 | Dystonia |
| D002547 | Cerebral Palsy |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D020820 | Dyskinesias |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001925 | Brain Damage, Chronic |