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| Name | Class |
|---|---|
| Sugar Nutrition, UK | UNKNOWN |
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The purpose of this study is to examine the effects of ingesting or mouth rinsing a sucrose (carbohydrate) versus a sucralose (carbohydrate-free) drink on self control, cognitive performance, and blood glucose level.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sucrose (50g) | Active Comparator | A 381g blackcurrant drink (cordial and water) providing 50g of sucrose |
|
| Sucralose (0.92 g sugars) | Placebo Comparator | A 381g blackcurrant drink (cordial and water) providing 0.92g of natural sugars |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ingestion of solution | Dietary Supplement | Participants will ingest the solution |
|
| Measure | Description | Time Frame |
|---|---|---|
| Capillary blood glucose change from baseline following rinsing or ingesting sucrose or sucralose solutions | Change from baseline in capillary blood glucose (assessed by lancet fingerprick and YSI blood glucose analyser) | - 30, -15, - 5, + 5, + 10, + 20, + 30, + 40 minutes relative to rinsing or ingestion of sucrose or sucralose solutions (each separated by 7 days in crossover manner) |
| Measure | Description | Time Frame |
|---|---|---|
| Visual verbal learning and memory performance following self-control depletion | Visual verbal learning performance will be assessed by the Visual Verbal Learning Test (Rey, 1964) following a self-control depletion task and ingestion or rinsing of a sucrose or sucralose solution | + 35 minutes post ingestion or rinsing of sucrose or sucralose solutions (each separated by 7 days in crossover manner) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Neil B Boyle | University of Leeds | Principal Investigator |
| Louise Dye | University of Leeds | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Human Appetite Research Unit (University of Leeds) | Leeds | LS29JT | United Kingdom |
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| Rinising of solution | Dietary Supplement | Participants rinse the solution in the oral cavity |
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| Attention switching performance following self-control depletion | Attention switching performance will be assessed by a switch task (Rogers and Monsell, 1995) following a self-control depletion task and ingestion or rinsing of a sucrose or sucralose solution | + 20 minutes post ingestion or rinsing of sucrose or sucralose solutions (each separated by 7 days in crossover manner) |
| Continuous blood glucose change from baseline following rinsing or ingesting sucrose or sucralose solutions | A subgroup of 10 participants recruited into the study will be fitted with a continuous glucose monitoring device (CGMS, iPRO) the day preceding each of the test days to measure continuous interstitial blood glucose levels | 24 hours preceding and during ingestion or rinsing of sucrose or sucralose solutions (each separated by 7 days in a crossover manner) |
| ID | Term |
|---|---|
| D000068356 | Self-Control |
| ID | Term |
|---|---|
| D012919 | Social Behavior |
| D001519 | Behavior |
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