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This is a validation study. A stroke symptom questionnaire will be adapted and translated into local language. Two community health workers will be trained in its administration. Their findings will be validated against assessment by two neurologists.
The study hypothesis is that the chance corrected agreement between the community worker administered stroke symptom questionnaire and the assessment by neurologist based on history and physical examination is at least moderate.
Overall Objective: To translate, adapt and validate a stroke symptom questionnaire for identification of stroke symptoms by community health workers ( CHW) in a peri-urban Pakistani community
Specific Aims:
The study will be conducted at the community site of AMAN community health project in Ibrahim Hyderi. Community health workers will systematically select households and from them individuals meeting eligibility criteria will be interviewed. Community workers will administer stroke symptom questionnaire to them at their homes. Those unable to answer will have a surrogate answering for them. In the second part of the study, two neurologists will independently assess all individuals. The purpose of this would be to validate the findings of the community workers based on the stroke symptom questionnaire.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pakistani adults | Men and women aged 40 and above, residing in Ibrahim Hyderi (periurban Pakistani community) Consenting to Interview about stroke symptoms |
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| Measure | Description | Time Frame |
|---|---|---|
| Validity | This was a validation study in which we calculated the sensitivity, specificity and predictive values for CHW administered questionnaire against assessment by two neurologists. We also assessed the chance corrected agreement (kappa) for the same. | Cross-sectional , All interviews within 4 Weeks ( CHW and Neurologist) |
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility | We assessed the feasibility of utilizing CHWs for stroke screening in terms of time taken to fill out questionnaire, difficulty in understanding questions and subject refusals | Cross sectional - All interviews within 4 weeks( CHW and Neurologists) |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of stroke symptoms | Once validated, we used the CHW administered tool to assess stroke symptom prevalence in this community | Cross-sectional _ All interviews within 4 weeks, by CHWS using validated questionairre |
Inclusion Criteria:
Exclusion Criteria:
- Individuals refusing to participate in any of the two components of the study i.e. CHW interview or neurological assessment
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Adults (above 40 years of age) residing in Ibrahim Hyderi and willing to participate in the all components of the study
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| Name | Affiliation | Role |
|---|---|---|
| Ayeesha K Kamal | AKUH | Study Director |
| Maria Khan | AKUH | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Community Health Center, Ibrahim Hyderi | Karachi | Sindh | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25825625 | Derived | Khan M, Kamal AK, Pasha O, Islam M, Azam I, Virk A, Nasir A, Andani A, Jan M, Akhtar A, Razzak JA. Study Protocol: Validation and Adaptation of community-worker-administered stroke symptom questionnaire in a periurban Pakistani community to determine disease burden. J Vasc Interv Neurol. 2015 Feb;8(1):1-10. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |