Electroencephalography Study Investigating the Effects of Vortioxetine in Healthy Male Subjects

Interventional, Randomised, Double-blind, Placebo-controlled, Active Comparator, Four-way Crossover Electroencephalography Study Investigating the Effects of Vortioxetine (Lu AA21004) in Healthy Male Subjects

To explore a neurophysiological marker (electroencephalography) of cognitive effect of vortioxetine

Inclusion Criteria:

• The subject has a normal resting EEG at screening visit
• The subject is able to perform tasks with an auditory stimulus
• The subject is not visually impaired - normal prescription glasses are accepted
• The subject has a normal circadian rhythm, defined as a person who usually wakes between 6:00 and 9:00 a.m. and goes to sleep between 9:00 pm and midnight.

Exclusion Criteria:

• The subject has worked shifts, including night duty, or has travelled across >3 time zones <2 weeks prior to the first dose of IMP.

Other inclusion and exclusion criteria may apply.