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The purpose of this study is to evaluate drugs interactions to compare pharmacokinetics in groups of monotherapy DW330SR, monotherapy DW1030, and coadministration DW330SR and DW1030
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A | Experimental | only DW330SR 45mg |
|
| B | Experimental | only DW1030 75mg |
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| C | Experimental | DW330SR 45mg and DW1030 75mg |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DW330SR 45mg | Drug |
| ||
| DW1030 75mg |
| Measure | Description | Time Frame |
|---|---|---|
| Trans-OH as Main Metabolites of DW330SR, DW330SR, Cmax, AUClast of DW1030 | -28 ~ -2day(screening), -1day, 1day, 2day |
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Inclusion Criteria:
Healthy Adult males aged 20~40 years at screening visit
Subjects with range of 19 kg/m2 ~ 27 kg/m2 as BMI measurements at screening visit
Subjects with BP range of below:
90 mmHg ≤ Systolic BP ≤ 140 mmHg 50 mmHg ≤ Diastolic BP ≤ 90mmHg
Subjects who voluntarily agreed with written consent that be able to understand the objective, method of the study, the characteristics of investigational drug, and comply with the reguirement of the study
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Asan Medical Center IRB | Seoul | South Korea |
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