Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Physiological and neurocognitive changes experienced as a result of increasing age may influence socioemotional functioning and economic behaviors, yet, the mechanisms through which these changes occur are not well understood. Studies have also shown that aerobic exercise may protect against age-related cognitive decline in other domains. This research is designed to test the hypothesis that aerobic exercise will enhance social, emotional and economic functioning in older adults, and that these effects will occur via the effect of exercise on neurocognitive structure and function assessed via magnetic resonance imaging (MRI). Advancing our knowledge of the mechanisms that influence emotional, social and economic functioning could inform the development of targeted treatments and prevention programs for older adults.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MICT + IT | Experimental | Moderate Intensity Continuous Training+Interval Training |
|
| LICT | Active Comparator | Low Intensity Continuous Training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Moderate Intensity Continuous Training+Interval Training | Behavioral |
|
| |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive Function |
| 4 months |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Colorado Boulder | Boulder | Colorado | 80309 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40259150 | Derived | Gust CJ, Martin-Willett R, Gibson LP, Giordano G, Seals DR, Bryan AD. Effects of aerobic exercise of different intensities on the social, emotional, and financial functioning of healthy older adults: results from a 16-week exercise randomized control trial. Geroscience. 2026 Feb;48(1):391-403. doi: 10.1007/s11357-025-01655-0. Epub 2025 Apr 21. | |
| 34062261 | Derived | Martin-Willett R, Morris B, Wilcox R, Giordano G, Andrews-Hanna J, Banich M, Bryan AB. The influence of a 16-week exercise program, APOE status, and age on executive function task performance: A randomized trial. Exp Gerontol. 2021 Sep;152:111431. doi: 10.1016/j.exger.2021.111431. Epub 2021 May 29. |
Not provided
Not provided
Not provided
| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| ICF | No | No | Yes | Informed Consent Form: Older Adult Consent Form | Dec 22, 2017 | May 20, 2019 | ICF_000.pdf |
| ICF | No | No | Yes | Informed Consent Form: Young Adult Consent Form | Oct 25, 2017 | May 20, 2019 | ICF_001.pdf |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Low Intensity Continuous Training |
| Behavioral |
|
|
| 33271506 | Derived | Martin-Willett R, Ellingson JE, Fries J, Helmuth T, Karoly H, Giordano G, Calhoun VD, Bryan AD. Few Structural Brain Changes Associated With Moderate-Intensity Interval Training and Low-Intensity Continuous Training in a Randomized Trial of Fitness and Older Adults. J Aging Phys Act. 2021 Jun 1;29(3):505-515. doi: 10.1123/japa.2019-0352. Epub 2020 Dec 2. |
| 32553024 | Derived | YorkWilliams SL, Gibson LP, Gust CJ, Giordano G, Hutchison KE, Bryan AD. Exercise Intervention Outcomes with Cannabis Users and Nonusers Aged 60 and Older. Am J Health Behav. 2020 Jul 1;44(4):420-431. doi: 10.5993/AJHB.44.4.5. |