The Use of Thromboelastometry (ROTEM) to Evaluate the Changes in Coagulation With Two Different Doses of Oxytocin Following Cesarean Delivery

The Use of Thromboelastometry (ROTEM) to Evaluate the Changes in Coagulation With Two Different Doses of Oxytocin Following Cesarean Delivery

The purpose of this study is to evaluate the differences in blood clotting seen in healthy patients given two different doses of oxytocin following cesarean delivery. The secondary objectives are to evaluate changes in blood pressure, rates of nausea and vomiting, and differences in blood loss with the two separate doses of oxytocin.

Inclusion Criteria:

• English speaking
• Age > or = 18 yrs
• Non-laboring women
• cesarean delivery under spinal anesthesia with pfannenstiel incision
• ASA I-III

Exclusion Criteria:

• Height <5'0"
• Allergy to phenylephrine
• Severe cardiac disease in pregnancy with marked functional limitations
• Women receiving NSAIDS, aspirin or other anticoagulants
• Subject enrollment in another study involving a study medication within 30 days of cesarean delivery
• Other physical or psychiatric condition which may impair the ability to cooperate with study data collection