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| Name | Class |
|---|---|
| University of Aarhus | OTHER |
| Harvard School of Public Health (HSPH) | OTHER |
| University of Copenhagen | OTHER |
| Ministry of Food, Agriculture and Fisheries, Denmark |
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The objective of this study is to test the effect of substitution dietary guidelines that are specifically aimed at the prevention of ischemic heart disease (IHD) on the dietary intake in the general Danish population.
225 participants will be included in the intervention. The intervention is planned to run for six months in a real life setting.
The study is a randomized, parallel dietary intervention study. Dietary intake, selected IHD biomarkers and anthropometric measurements will be measured at two visits during the intervention period as well as 6 months after the end of the intervention. The study includes a baseline visit followed by a visit where web based dietary records will be completed by the subjects and blood samples and anthropometrics will be measured.
The intervention will consist of information on dietary advice due to the specific IHD dietary guideline or the current national dietary guidelines. The information will be provided to the participants via leaflets and recipes.
After the baseline visit the subjects will be randomized to group A, B or C: In group A the subjects will receive dietary advice, according to the specific IHD dietary guideline, in group B the subjects will receive dietary advice according to the current national dietary guidelines and in group C the subjects will be instructed to follow their normal dietary habits.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DIPI: Danish national dietary guidelines | Active Comparator | The subjects will receive dietary advice according to the current national dietary guidelines |
|
| DIPI: Specific IHD dietary guideline | Active Comparator | The subjects will receive dietary advice, according to the specific ischemic heart disease dietary guidelines. |
|
| Normal dietary habits | No Intervention | The Subjects will be instructed to follow their normal dietary habits |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DIPI | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Dietary intake | Dietary intake will be measured at two visits during the intervention period as well as 6 months after the end of the intervention. | 6 month |
| Measure | Description | Time Frame |
|---|---|---|
| Selected ischemic heart disease biomarkers and anthropometric measurements | Selected IHD biomarkers and anthropometric measurements will be measured at two visits during the intervention period as well as 6 months after the end of the intervention. | 6 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Inge Tetens, Professor | Technical University of Denmark | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Technical University of Denmark | Søborg | Denmark | 2860 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32827219 | Derived | Hooper L, Martin N, Jimoh OF, Kirk C, Foster E, Abdelhamid AS. Reduction in saturated fat intake for cardiovascular disease. Cochrane Database Syst Rev. 2020 Aug 21;8(8):CD011737. doi: 10.1002/14651858.CD011737.pub3. | |
| 32428300 | Derived | Hooper L, Martin N, Jimoh OF, Kirk C, Foster E, Abdelhamid AS. Reduction in saturated fat intake for cardiovascular disease. Cochrane Database Syst Rev. 2020 May 19;5(5):CD011737. doi: 10.1002/14651858.CD011737.pub2. |
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| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| ID | Term |
|---|---|
| C014364 | 4',6-bis(2'imidazolinyl-4',5'-H)-2-phenylindole |
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| UNKNOWN |
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| 29352831 | Derived | Arentoft JL, Hoppe C, Andersen EW, Overvad K, Tetens I. Associations between adherence to the Danish Food-Based Dietary Guidelines and cardiometabolic risk factors in a Danish adult population: the DIPI study. Br J Nutr. 2018 Mar;119(6):664-673. doi: 10.1017/S0007114517003695. Epub 2018 Jan 21. |