Study Design : randomized, open label, single-dose, 2-way cross-over design

Phase : Phase I

Inclusion Criteria:

• healthy volunteers between the ages of 19 to 55 years old
• 19 ≤ BMI ≤ 27
• having neither congenital/chronic diseases nor pathological symptoms/findings as results of medical examination
• doctor determines to be suitable as subjects within 4 weeks ago before administration

Exclusion Criteria:

• Hypersensitivity(or history of hypersensitivity) to amlodipine and olmesartan
• Exceed 1.5 times of the upper limit of the reference range of AST, ALT, total bilirubin, γ-GT
• Excessive drinking(exceed alcohol 140g/week)
• Excessive caffeine(exceed 4cups/day) and grape fruit/orange juice(exceed 1cup/day)
• Smoking over 10 cigarettes per day