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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-A01213-42 | Other Identifier | RCB number |
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The primary objective of this study is to estimate the distribution of pathogenic species and genotypes of bacterial diversity in 7 stages ICDAS (International Caries Detection and Assessment System) corresponding to the severity of dental caries among patients aged 3-45 years consulting in the Dentistry Departments of the Nîmes University Hospital and the Montpellier University Hospital.
Secondary objectives include:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 3 to 16 years of age | Volunteers of 3 to 16 years of age, coming in to the hospital for a dental consultation. See inclusion/exclusion criteria. Intervention: Dental cavity evaluation Intervention: Saliva sampling Intervention: Plaque sampling |
| |
| 17 - 45 years of age | Volunteers of 17 to 45 years of age, coming in to the hospital for a dental consultation. See inclusion/exclusion criteria. Intervention: Dental cavity evaluation Intervention: Saliva sampling Intervention: Plaque sampling |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dental cavity evaluation | Other | The dental cavities present will be evaluated using the ICDAS (International Caries Detection and Assessment System). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Bacterial profile | Bacterial profiles will be constructed using saliva and plaque samples. | Baseline (day 0) |
| ICDAS assessment | Dental caries will be assessed using the ICDAS (International Caries Detection and Assessment System) system | Baseline (day 0) |
| Measure | Description | Time Frame |
|---|---|---|
| Studies were stopped during high school? yes/no | baseline (Day 0) | |
| Does the patient have at least five fillings? yes/no | Baseline (day 0) | |
| Does the patient have at least one filling and one missing tooth on the anterior sector following the carious lesion? yes/no |
| Measure | Description | Time Frame |
|---|---|---|
| Profession (or parents' professions) | baseline (day 0) | |
| Age | baseline (day 0) | |
| Sex |
Inclusion Criteria:
Exclusion Criteria:
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Volunteers aged 3 to 45 who come in to the hospital for a dental consultation.
Patients are recruted according to age in order to form two groups: 1/2 of participants will be between 3 and 16 years of age; the other half of participants will be between 17 and 45 years of age.
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| Name | Affiliation | Role |
|---|---|---|
| Hervé Léon, MD | Centre Hospitalier Universitaire de Nīmes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU de Montpellier - Centre de Soins, d'Enseignement et de Recherche Dentaires | Montpellier | 34295 | France | |||
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| ID | Term |
|---|---|
| D003731 | Dental Caries |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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Plaque and saliva samples; DNA analysis is aimed at describing microbial communities.
| Saliva sampling | Biological | A saliva sample will be harvested. |
|
| Plaque sampling | Biological | Plaque samples from a healthy tooth and a tooth with a cavity will be harvested. |
|
| baseline (day 0) |
| Within the last 12 months, the patient has had dental care or tooth removal following the carious lesion? yes/no | baseline (day 0) |
| Yesterday, did the patient eat at least three snacks (or sugary or carbonated drinks) between meals? yes/no | Baseline (day 0) |
| Yesterday, did the patient brush his/her teeth fewer than 2 times? yes/no | baseline (day 0) |
| The patient has at least one carious lesion restricted to the enamel? yes/no | baseline (day 0) |
| The patient has at least one carious lesion restricted to the enamel on an anterior tooth or involving the smooth surface on a posterior tooth (yes/no) | baseline (day 0) |
| The patient has at least one carious lesion attacking the dentin or pulp. yes/no | baseline (day 0) |
| The patient has at least one carious lesion reaching dentin or pulp on an anterior tooth or on the smooth surface of a posterior tooth (yes/no) | baseline (day 0) |
| baseline (day 0) |
| CHRU de Montpellier - Hôpital La Colombière |
| Montpellier |
| 34295 |
| France |
| CHRU de Nîmes - Hôpital Universitaire Carémeau | Nîmes | 30029 | France |