Immediate Implant Breast Reconstruction

Immediate Implant Breast Reconstruction for Patients With Mastectomy Ans Post opérative Chest Wall Radiotherapy

The purpose of this study is to study the impact of the immediate implant breast reconstruction for patients with mastectomy and postoperative chest wall radiotherapy

non applicable

Inclusion Criteria:

• Histologically confirmed breast carcinoma
• Patients planned for mastectomy with immediate single stage breast reconstruction using an acellular dermal matrix (Strattice™, LifeCell Corporation)
• Patients planned to receive postoperative chest wall irradiation
• Age ≥ 18 years old
• WHO performance status 0-1
• Affiliation to a social security system
• Informed consent signed prior any study specific procedures

Exclusion Criteria:

• Inflammatory breast cancer
• Tumors with extensive involvement of the skin
• Use of tissue expander
• Indication of postoperative chemotherapy
• Patients planned for bilateral mastectomy
• History of previously treated ipsilateral breast carcinoma
• Usual contraindications for ADM
• Medical debility precluding surgical treatment
• Psychological, social, geographical disorders or any other condition that would preclude study compliance (treatment modalities and study follow-up).
• Pregnancy or breast feeding
• Inability to attend or comply with interventions or follow-up scheduling, disability or difficulty preventing a proper understanding of trial instructions
• Legal inability or restricted legal ability