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| Name | Class |
|---|---|
| University Hospital, Rouen | OTHER |
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Since 20 years, the techniques of direct measurement of cardiac stiffness in the diagnosis of myocardial diseases do not exist.
We propose a human study evaluating the direct measurement of cardiac ultrasound stiffness by elastography.
This study will include 30 patients with cardiac disease whose rigidity varies with underlying disease.
The purpose of this study is to evaluate the stiffness during open heart surgery.
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| Measure | Description | Time Frame |
|---|---|---|
| Young's Modulus measurement according to the equation E = Young 3ρCs ² | Ultrasound acquisition will be completed in epicardial vue using a linear probe SuperLinear 15-4 ™ connected to an ultrasound (AixplorerTM ® from Supersonic Imagine). The acquisitions will be completed in mode B + Elastrography Shear Wave ™ (SWE). A sterile gel is deposited in the bottom of the pouch of sterile protection of the probe. Many measurements will be done on accessible left and right ventricle areas. Measurement of Young's modulus: automated by the onboard model according to the equation E = Young 3ρCs ², where E is the Young's elastic modulus software, ρ is the tissue density and Cs the velocity of shear wave | During herat surgery (Day 0) |
| Measure | Description | Time Frame |
|---|---|---|
| diastolic function parameters | Correlation between young's modulus and diastolic function parameters is assess after surgery by post processing | Day 0 |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutive patients undergoing cardiac surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eric Saloux, MD | Contact | +330231064901 | saloux-e@chu-caen.fr | |
| Fabrice Bauer, MD,PhD | Contact | fabrice.bauer@chu-rouen.fr |
| Name | Affiliation | Role |
|---|---|---|
| Fabrice Bauer, MD,PhD | University Hospital, Rouen | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Caen University Hospital | Recruiting | Caen | Basse Normandie | 14033 | France |
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