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| Name | Class |
|---|---|
| European Union | OTHER |
| Odense University Hospital | OTHER |
| University of Pittsburgh | OTHER |
| National Institute on Aging (NIA) |
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active life-style intervention | Experimental | The "active life-style intervention" is designed as 12-week structured and progressive heavy-resistance power training combined with recommended everyday physical activity. |
|
| Control | No Intervention | The control group is offered to enroll in the same active life-style intervention after the end of the 12-week control period. During the control period this group is asked to maintain the habitual life style. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Active life-style intervention | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in leg press muscle power | Muscle power will be assessed on the dominant leg with the Notthingham power rig and expressed as Watt/kg. Subjects are sitting with | Changes in muscle power from baseline to 12-week follow up |
| Measure | Description | Time Frame |
|---|---|---|
| Physical activity, sedentary behaviour and sleep quality (objectively assessed by accelerometry) | Changes from baseline to 12-week follow up | |
| Cognitive function (Mini Mental State Examination and Digit Symbol Substitution Test) | Changes from baseline to 12-week follow up |
| Measure | Description | Time Frame |
|---|---|---|
| Use of public health care resources | 5-year retrospectively and 3-year prospectively |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Paolo Caserotti, PhD | University of Southern Denmark | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Southern Denmark, Department of Sports Science and Clinical Biomechanics | Odense | 5230 M | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39729186 | Derived | Muollo V, Hvid LG, Shanbhogue VV, Steinhauser V, Caporossi D, Dimauro I, Andersen MS, Fantini C, Grazioli E, Strotmeyer ES, Caserotti P. Effects of 12-week power training on bone in mobility-limited older adults: randomised controlled trial. Arch Osteoporos. 2024 Dec 27;20(1):5. doi: 10.1007/s11657-024-01487-z. |
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| NIH |
| Maastricht University | OTHER |
| University of Washington | OTHER |
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| Self-report Health-related measures including quality of life, pain, depression, sleep quality, fatigue, activities of daily living, anxiety. | Changes from baseline to 12-week follow up |
| Body composition including muscle, fat and bone quantity and quality | Changes from baseline to 12-week follow up |
| Neuromuscular function including strength, power, explosive force, postural control, motor/sensor nerve function | Changes from baseline to 12-week follow up |
| Selected blood biomarkers related to physical, muscle-skeletal and cognitive function (e.g. C reactive protein, insulin like growth factor, IL-6, BDNF) | Changes from baseline to 12-week follow up |
| Physical function including short and long distance walking speed, stair climbing, Short Physical Performance Battery Test | Changes from baseline to 12-week follow up |